4271-96-9 Usage
Description
1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine is an organic compound belonging to the class of pyrimidines, which are heterocyclic compounds with a six-membered ring containing four nitrogen atoms. This specific compound is characterized by the presence of two methyl groups attached to the first and second carbon atoms of the ring, making it a derivative of tetrahydropyrimidine. It is a versatile reagent in the field of organic synthesis and has potential applications in various industries due to its unique chemical properties.
Uses
1. Used in Pharmaceutical Industry:
1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine is used as a reagent for the synthesis of pyrantel derivatives, which possess nematocidal activity. These derivatives are essential in the development of drugs and treatments targeting nematodes, or roundworms, which are parasites that can cause various diseases in humans and animals.
2. Used in Chemical Research:
1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine is also used as a reactant in the preparation of hapten antibodies that evoke terpenoid cyclization. Terpenoids are a large and diverse class of organic compounds that play a crucial role in the biochemistry of plants and animals. The cyclization of terpenoids is an essential process in the synthesis of various natural products, and 1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine plays a vital role in facilitating this process.
Check Digit Verification of cas no
The CAS Registry Mumber 4271-96-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,7 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4271-96:
(6*4)+(5*2)+(4*7)+(3*1)+(2*9)+(1*6)=89
89 % 10 = 9
So 4271-96-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H12N2/c1-6-7-4-3-5-8(6)2/h3-5H2,1-2H3
4271-96-9Relevant articles and documents
Synthesis and menatocidal activities of arylvinyltetrahydropyrimidines
Kraouti,Caujolle,Labidalle,Payard,Bories,Loiseau,Gayral
, p. 979 - 982 (1993)
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Synthesis method of 1,2-dimethyl-1,4,5,6-tetrahydropyrimidine
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Paragraph 0025; 0028; 0031; 0032; 0037; 0042; 0047-0057, (2018/11/27)
The invention discloses a synthesis method of 1,2-dimethyl-1,4,5,6-tetrahydropyrimidine. A novel route is chosen, reactions are efficiently and quickly carried out under the assistance of microwaves,and the product yield is high. The synthesis method has the advantages of simple reaction route, easy operation, short reaction time, and high yield.
Push-pull alkenes by reacting N,N′-dimethyl cyclic ketene N,N′-acetals with isocyanates: synthesis, structures, and reactivities
Ye, Guozhong,Henry, William P.,Chen, Chunlong,Zhou, Aihua,Pittman Jr., Charles U.
supporting information; experimental part, p. 2135 - 2139 (2009/07/26)
N,N′-Dimethyl cyclic ketene N,N′-acetals react with two or three equivalents of isocyanates to generate tetrasubstituted push-pull alkene derivatives in one-pot sequential reactions. X-ray crystallography showed significant elongations and out of plane distorsions of the polarized carbon-carbon double bonds.