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Metalation/functionalization sequences applied to 2-bromo-3- fluoroquinolines
Ondi, Levente,Volle, Jean-No?l,Schlosser, Manfred
, p. 717 - 725 (2007/10/03)
Mono- and disubstituted 2-bromo-3-fluoroquinolines 3 are readily accessible. They can be converted into the 3-fluoroquinoline-2-carboxylic acids 5 by consecutive halogen/metal permutation and into the 2-bromo-3- fluoroquinoline-4-carboxylic acids 6 by con
