83501-30-8

Upstream product

• 119-61-9 benzophenone 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 925-90-6 ethylmagnesium bromide 
• 100-52-7 benzaldehyde 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 

Downstream Products

• 74-86-2 acetylene 
• 1393371-07-7 (4-(2,2-diphenylvinyl)-2-(4-methoxyphenyl)-5-phenylfuran-3-yl)(4-methoxyphenyl)methanone 
• 1393371-09-9 2,3,5-triphenylfuran 
• 6307-20-6 2,3,5-triphenylfuran 
• 1393370-73-4 (4-(2,2-diphenylvinyl)-2,5-diphenylfuran-3-yl)(phenyl)methanone 
• 1393371-08-8 1-(4-(2,2-diphenylvinyl)-2-methyl-5-phenylfuran-3-yl)(4-methoxyphenyl)methanone 
• 1393371-06-6 (4-(2,2-diphenylvinyl)-2-methyl-5-phenylfuran-3-yl)(phenyl)methanone 

Relevant academic research and scientific papers

Bronsted acid-catalyzed cycloisomerization of but-2-yne-1,4-diols with or without 1,3-dicarbonyl compounds to tri- and tetrasubstituted furans

A Bronsted acid-catalyzed method to prepare tri- and tetrasubstituted furans efficiently from cycloisomerization of but-2-yne-1,4-diols with or without 1,3-dicarbonyl compounds is described. By taking advantage of the orthogonal modes of reactivity of the alcoholic substrate through slight modification of the reaction conditions, a divergence in product selectivity was observed. At room temperature, p-TsOH?H 2O-mediated tandem alkylation/cycloisomerization of the propargylic 1,4-diol with the β-dicarbonyl compound was found to selectively occur to provide the tetrasubstituted furan product. On the other hand, increasing the reaction temperature to 80 °C was discovered to result in preferential p-TsOH?H2O-catalyzed dehydrative rearrangement of the unsaturated alcohol and formation of the 2,3,5-trisubstituted furan adduct.

Applications of Phase Transfer Catalysis, 24. - Note on the Acceleration of Reactions between Alkynes and Carbonyl Compounds

Reactions between the title compounds in toluene/15percent aqueous sodium hydroxide are accelerated by the presence of N(C4H9)Br.