83505-21-9Relevant articles and documents
SYNTHESIS AND INTRAMOLECULAR CYCLISATION OF ortho-HYDROXY-2,3,3,3-TETRAFLUOROPROPIOPHENONE. FORMATION OF 3-FLUORO-4-HYDROXYCOUMARIN
Dmowski, Wojciech
, p. 589 - 598 (1982)
Acidic hydrolysis of 1-(o-methoxyphenyl)pentafluoropropene 1 gave o-hydroxy-2,3,3,3-tetrafluoropropiophenone 2 and o-methoxy-2,3,3,3-tetrafluoropropiophenone 3.Compound 2 when treated with aqueous potassium hydroxide or methanolic sodium methoxide gave 3-fluoro-4-hydroxycoumarin 4.Structure of 4 has been established by spectral means and some chemical reactions.The cyclisation mechanism of 2 is discussed.