83520-54-1Relevant academic research and scientific papers
Studies on Pyrazines. Part 27. A New Deoxidative Nucleophilic Substitution of Pyrazine N-Oxides; Synthesis of Azidopyrazines with Trimethylsilyl Azide
Sato, Nobuhiro,Miwa, Naoko,Hirokawa, Noriko
, p. 885 - 888 (2007/10/02)
Azidopyrazines bearing amino, methoxy and/or phenylgroups have been synthesized by reaction of pyrazine N-oxides with trimethylsilyl azide in the presence of diethylcarbamoyl chloride in refluxing acetonitrile.In most cases, the azidation occurs only at t
Syntheses and Reactions of Some 2,3-Disubstituted Pyrazine Monoxides
Watahiki, Hiroko,Tsutsui, Mayumi,Akita, Yasuo,Watanabe, Tokuhiro,Kurihara, Teruo
, p. 465 - 473 (2007/10/02)
The reactions of 2,3-dimethyl- (4), 2,3-diphenyl- (6), and 2-methyl-3-phenyl-pyrazine monoxides (8 and 9) with phosphoryl chloride and acetic anhydride resulted in giving monochloro- and monoacetoxy-pyrazines in almost all cases.However, the reaction of 6 with acetic anhydride afforded exceptionally a diacetoxydihydropyrazine.These products were converted further to hydroxy or dichloro derivatives.
