61578-13-0

Basic information

• Product Name: Pyrazine, 2,3-diphenyl-, 1-oxide
• Synonyms: 2,3-Diphenyl-pyrazin-1-oxid;Pyrazine,2,3-diphenyl-,1-oxide;2,6-diphenylpyrazine 1-oxide;2,3-diphenylpyrazine 1-oxide
• CAS NO: 61578-13-0
• Molecular Formula: C16H12N2O
• Molecular Weight: 248.284
• Mol File: 61578-13-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 171-172 °C
• Boiling Point: 460.6±33.0 °C(Predicted)
• Density: 1.14±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Pyrazine, 2,3-diphenyl-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, 2,3-diphenyl-, 1-oxide(61578-13-0)
• EPA Substance Registry System: Pyrazine, 2,3-diphenyl-, 1-oxide(61578-13-0)

Safety Data

• Hazardous Substances Data: 61578-13-0(Hazardous Substances Data)

Upstream product

• 134-81-6 benzil 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 107-15-3 ethylenediamine 
• 1489-06-1 2,3-diphenyl-5,6-dihydropyrazine 
• 595-90-4 tetraphenyltin(IV) 
• 78754-79-7 2-chloro-5,6-diphenylpyrazine 1-oxide 
• 83520-54-1 2-chloro-5,6-diphenylopyrazine 4-oxide 
• 1588-89-2 2,3-diphenylpyrazine 

Downstream Products

• 135510-34-8 5,6-diphenyl-2-(p-toluoyl)pyrazine 1-oxide 
• 135510-46-2 5,6-diphenyl-2-formylpyrazine 1-oxide 
• 83520-59-6 Acetic acid 3-acetoxy-5,6-diphenyl-2,3-dihydro-pyrazin-2-yl ester 
• 135510-42-8 5,6-diphenyl-2-(α-hydroxybenzyl)pyrazine 1-oxide 
• 135510-38-2 5,6-diphenyl-2-(α-hydroxypropyl)pyrazine 1-oxide 
• 76849-26-8 2-azido-5,6-diphenylpyrazine 
• 102659-57-4 2,3-diphenyl-5-piperidino-pyrazine 
• 41270-66-0 2-chloro-5,6-diphenylpyrazine 
• 83520-60-9 5-Acetoxy-2,3-diphenylpyrazine 
• 83520-54-1 2-chloro-5,6-diphenylopyrazine 4-oxide 
• 57038-62-7 5,6-Dichloro-2,3-diphenylpyrazine 
• 18591-57-6 2,3-Diphenyl-6-hydroxypyrazine 

Relevant articles and documents

γ-Maghemite-silica nanocomposite: A green catalyst for diverse aromatic N-heterocycles

γ-Maghemite-silica nanocomposite has been applied as a green catalyst to synthesize variety of aromatic N-heterocycles under solvent free conditions. Characterization was done by modern analytical tools (UV, IR, AAS, DSC, EDXRF, powdered XRD, EPR, Mo?ssbauer and TEM). Mild reaction conditions and recyclability have made the present protocol both environmentally and economically viable.

COUPLING REACTION OF CHLOROPYRAZINES AND THEIR N-OXIDES WITH TETRAPHENYLTIN

By the coupling reaction of monochloropyrazines, dichloropyrazines, 2-chloropyrazine 1-oxides, and 2-chloropyrazine 4-oxides with tetraphenyltin, the corresponding phenylpyrazines were prepared in satisfactory yields.

Syntheses and Reactions of Some 2,3-Disubstituted Pyrazine Monoxides

The reactions of 2,3-dimethyl- (4), 2,3-diphenyl- (6), and 2-methyl-3-phenyl-pyrazine monoxides (8 and 9) with phosphoryl chloride and acetic anhydride resulted in giving monochloro- and monoacetoxy-pyrazines in almost all cases.However, the reaction of 6 with acetic anhydride afforded exceptionally a diacetoxydihydropyrazine.These products were converted further to hydroxy or dichloro derivatives.