83541-21-3

Upstream product

• 83479-86-1 methyl 3-(methylthio)-4,6-dioxo-5-phenyl-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 941-69-5 N-phenyl-maleimide 
• 58091-08-0 methyl N-(bis(methyl)thiomethilene)glycinate 

Downstream Products

• 83479-86-1 methyl 3-(methylthio)-4,6-dioxo-5-phenyl-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylate 

Relevant academic research and scientific papers

Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants

The 1,3-dipolar cycloaddition to N-phenylmaleimide of azomethine ylides, generated in situ from sulfanyl-substituted imines of glycine esters, yields 5H-dihydro-pyrrolo products with syn diastereoselectivity. The syn (major) and anti (minor) products were

X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES. CYCLOADDITIONS OF THIOIMINOETHERS AND THIOIMINOCARBONATES

Thioiminoethers and thioiminocarbonates of α-amino acid esters undergo acetic acid catalysed cycloaddition reactions with N-phenylmaleimide via their 1,3-dipolar tautomers.