58091-08-0

Basic information

• Product Name: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER
• Synonyms: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER;LABOTEST-BB LT00453321;Methyl 2-(bis(Methylthio)MethyleneaMino)acetate
• CAS NO: 58091-08-0
• Molecular Formula: C₆H₁₁NO₂S₂
• Molecular Weight: 193.29
• Product Categories: Glycine Derivatives;Peptide Synthesis;Unnatural Amino Acid Derivatives
• Mol File: 58091-08-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 259°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.217 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0133mmHg at 25°C
• Refractive Index: n20/D 1.547(lit.)
• PKA: 1.35±0.50(Predicted)
• CAS DataBase Reference: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER(58091-08-0)
• EPA Substance Registry System: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER(58091-08-0)

Safety Data

• RIDADR: UN 3334
• WGK Germany: 3
• Hazardous Substances Data: 58091-08-0(Hazardous Substances Data)

Usage

General Description

N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER is a chemical compound with the molecular formula C6H13NO3S2. It is a methyl ester derivative of N-[bis(methylthio)methylene]glycine, which is a derivative of glycine and contains sulfur atoms. N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER is commonly used in organic synthesis and pharmaceutical research. It has potential pharmacological properties and may be utilized in the development of new drugs. Additionally, it is used as a building block in the synthesis of various organic compounds. However, it is important to handle this chemical with caution and ensure proper safety measures are in place due to its potential hazards.

InChI:InChI=1/C6H11NO2S2/c1-9-5(8)4-7-6(10-2)11-3/h4H2,1-3H3

Upstream product

• 75-15-0 carbon disulfide 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 74-88-4 methyl iodide 
• 616-34-2 methoxycarbonylmethylamine 
• 58091-06-8 methylsulphanylthiocarbonylaminoacetic acid methyl ester 

Downstream Products

• 142311-83-9 Methyl N-(methylthiocarbonyl)glycinate 
• 340039-87-4 C₁₅H₂₂N₂O₂S₂ 
• 83479-86-1 methyl 3-(methylthio)-4,6-dioxo-5-phenyl-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 83479-86-1 methyl 3-(methylthio)-4,6-dioxo-5-phenyl-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 108437-95-2 (2S,5S)-N-<(S)-N-bis(methylthio)methylene-O-methylthyrosyl>-2,5-bis(methoxymethoxymethyl)pyrrolidine 
• 108437-95-2 C₂₃H₃₆N₂O₆S₂ 
• 108437-92-9 (2S,5S)-N-<(S)-N-bis(methylthio)methylenephenylalanyl>-2,5-bis(methoxymethoxymethyl)pyrrolidine 
• 76862-27-6 2-Methylsulfanyl-1-phenyl-1H-imidazole-4-carboxylic acid methyl ester 
• 76862-26-5 2-(methylthio)-4-thiazolecarboxylic acid methyl ester 
• 161264-10-4 (2R)-N-<(2S)-6--2-<amino>hexanoyl>bornane-10,2-sultam 
• 161264-09-1 (2R)-N-<(2S)-5--2-<amino>pentanoyl>bornane-10,2-sultam 
• 161264-12-6 (2R)-N-<(2S)-2-<amino>-6-(N-phenyl-N-tosylamino)-hexanoyl>bornane-10,2-sultam 
• 161264-14-8 (2R)-N-<(2S)-8-<(benzyloxycarbonyl)amino>-2-<amino>octanoyl>bornane-10,2-sultam 
• 161264-11-5 (2R)-N-<(2S)-6--2-<amino>hexanoyl>bornane-10,2-sultam 

Relevant articles and documents

Eco-friendly synthesis of novel thiohydantoin-type sulfur-containing imidazolinone derivatives from glycine ester

[Figure not available: see fulltext.] Imino derivatives of glycine ester were prepared from methyl glycinate by the known procedure and then they reacted with several amines under microwave irradiation without solvent that gave the corresponding glycine a

Triphosgene: A versatile reagent for the synthesis of azetidin-2-ones

An efficient use of triphosgene, as an acid activator, for the synthesis of substituted azetidin-2-ones via ketene-imine cycloaddition reaction using various acids and imines have been described.

Unique zeolite-catalyzed synthesis of nitroketene S,N-acetals

Dimethyl carbonimidodithioates (4a-g, 7a-c) derived from various primary amines and amino acid esters [glycine, (L)-alanine and (L)-phenylalanine] have been condensed with nitromethane in the presence of the rare-earth exchanged zeolite RE(70%)Na Y to give the S,N-acetals (5a-g, 8a-c). Mercuric chloride catalyzed hydrolysis of these (8a-c) has led to the nitroacetyl derivatives (9a-c). The glycine derivative (7a) gives a dimeric product (11) when heated alone with the zeolite.