58091-08-0

Basic information

• Product Name: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER
• Synonyms: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER;LABOTEST-BB LT00453321;Methyl 2-(bis(Methylthio)MethyleneaMino)acetate
• CAS NO: 58091-08-0
• Molecular Formula: C₆H₁₁NO₂S₂
• Molecular Weight: 193.29
• Product Categories: Glycine Derivatives;Peptide Synthesis;Unnatural Amino Acid Derivatives
• Mol File: 58091-08-0.mol

Chemical Properties

• Boiling Point: 259°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.217 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0133mmHg at 25°C
• Refractive Index: n20/D 1.547(lit.)
• PKA: 1.35±0.50(Predicted)
• CAS DataBase Reference: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER(58091-08-0)
• EPA Substance Registry System: N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER(58091-08-0)

Safety Data

• RIDADR: UN 3334
• WGK Germany: 3
• Hazardous Substances Data: 58091-08-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER is used as a research compound for its potential pharmacological properties, contributing to the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER is used as a building block for the synthesis of various organic compounds, facilitating the creation of diverse chemical structures.
Used in Chemical Production:
N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER is utilized in the production of certain chemicals, where its unique structure and properties are beneficial for specific applications.
Safety Considerations:
It is crucial to handle N-[BIS(METHYLTHIO)METHYLENE]GLYCINE METHYL ESTER with care and implement proper safety measures due to its potential hazards, ensuring the well-being of individuals and the environment.

InChI:InChI=1/C6H11NO2S2/c1-9-5(8)4-7-6(10-2)11-3/h4H2,1-3H3

Upstream product

• 58091-06-8 methylsulphanylthiocarbonylaminoacetic acid methyl ester 
• 74-88-4 methyl iodide 
• 75-15-0 carbon disulfide 
• 616-34-2 methoxycarbonylmethylamine 
• 5680-79-5 glycine ethyl ester hydrochloride 

Downstream Products

• 142311-83-9 Methyl N-(methylthiocarbonyl)glycinate 
• 1212-53-9 methyl N-benzyloxycarbonylglycinate 
• 127556-03-0 (2R)-N-{N-[bis(methylthio)methylidene]glycyl}bornane-10,2-sultam 
• 340039-87-4 C₁₅H₂₂N₂O₂S₂ 
• 127556-05-2 (2R)-N-<(2S)-2-<amino>-3-phenylpropan-1-oyl>bornane-10,2-sultam 
• 161264-13-7 (2R)-N-<(2S)-7-<(benzyloxycarbonyl)amino>2-<amino>heptanoyl>bornane-10,2-sultam 
• 161264-11-5 (2R)-N-<(2S)-6--2-<amino>hexanoyl>bornane-10,2-sultam 
• 161264-14-8 (2R)-N-<(2S)-8-<(benzyloxycarbonyl)amino>-2-<amino>octanoyl>bornane-10,2-sultam 
• 161264-12-6 (2R)-N-<(2S)-2-<amino>-6-(N-phenyl-N-tosylamino)-hexanoyl>bornane-10,2-sultam 
• 161264-09-1 (2R)-N-<(2S)-5--2-<amino>pentanoyl>bornane-10,2-sultam 
• 161264-10-4 (2R)-N-<(2S)-6--2-<amino>hexanoyl>bornane-10,2-sultam 
• 83479-86-1 methyl 3-(methylthio)-4,6-dioxo-5-phenyl-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 83479-86-1 methyl 3-(methylthio)-4,6-dioxo-5-phenyl-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylate 

Relevant articles and documents

Eco-friendly synthesis of novel thiohydantoin-type sulfur-containing imidazolinone derivatives from glycine ester

[Figure not available: see fulltext.] Imino derivatives of glycine ester were prepared from methyl glycinate by the known procedure and then they reacted with several amines under microwave irradiation without solvent that gave the corresponding glycine a

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The 1,3-dipolar cycloaddition to N-phenylmaleimide of azomethine ylides, generated in situ from sulfanyl-substituted imines of glycine esters, yields 5H-dihydro-pyrrolo products with syn diastereoselectivity. The syn (major) and anti (minor) products were

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An efficient use of triphosgene, as an acid activator, for the synthesis of substituted azetidin-2-ones via ketene-imine cycloaddition reaction using various acids and imines have been described.

Stereospecific Synthesis of N--α,β-Didehydroamino Acid Methyl Esters, New Synthons in the Synthesis of α-Amino Acids

N--α,β-didehydroamino acid methyl esters 4a-c have been prepared with total geometric selectivity from easily accesible β-hydroxyamino acids through N--β-hydroxyamino acid methyl esters 3a-c as intermediates.The (E)-isomers can be easily converted into the corresponding (Z)-isomers in the presence of a catalytic amount of titanium (IV) chloride. Key words: Stereospecific dehydration, stereoisomers, didehydroamino acids, amino acids, E-Z isomerization

Unique zeolite-catalyzed synthesis of nitroketene S,N-acetals

Dimethyl carbonimidodithioates (4a-g, 7a-c) derived from various primary amines and amino acid esters [glycine, (L)-alanine and (L)-phenylalanine] have been condensed with nitromethane in the presence of the rare-earth exchanged zeolite RE(70%)Na Y to give the S,N-acetals (5a-g, 8a-c). Mercuric chloride catalyzed hydrolysis of these (8a-c) has led to the nitroacetyl derivatives (9a-c). The glycine derivative (7a) gives a dimeric product (11) when heated alone with the zeolite.

3,3,3-TRIFLUORO-2-MERCAPTOMETHYL-N-TETRAZOLYL SUBSTITUTED PROPANAMIDES AND METHOD OF USING SAME

Compounds of the formula STR1 wherein Y can be tetrazolyl are disclosed. These compounds are useful as cardiovascular agents.