83548-49-6

Basic information

• Product Name: 1,2-Pyrrolidinedicarboxylic acid, 4-iodo-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-
• CAS NO: 83548-49-6
• Molecular Formula: C11H18INO4
• Molecular Weight: 355.173
• Mol File: 83548-49-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-iodo-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-iodo-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-(83548-49-6)
• EPA Substance Registry System: 1,2-Pyrrolidinedicarboxylic acid, 4-iodo-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-(83548-49-6)

Safety Data

• Hazardous Substances Data: 83548-49-6(Hazardous Substances Data)

Usage

Carboxylic Acid

The presence of -COOH groups in the molecule.

Ester

The presence of an ester group (-COO-) in the molecule.

Iodine

The presence of an iodine atom in the molecule.

Chirality

The molecule has chiral centers, which means it has non-superimposable mirror images (enantiomers).

Biological Activity

The specific stereochemistry of the compound may influence its interaction with biological targets, such as enzymes or receptors.

Applications

Potential applications in organic synthesis, pharmaceuticals, and biochemical research due to its unique structure and stereochemistry.

Solubility

The solubility of the compound may vary depending on the solvent used, but it is likely to be more soluble in organic solvents like ethanol or methanol.

Stability

The compound may be sensitive to certain conditions, such as light, heat, or moisture, which could affect its stability and reactivity.

Synthesis

The compound can be synthesized through various chemical reactions, such as esterification, substitution, or condensation reactions, depending on the desired stereochemistry and functional groups.

Upstream product

• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 

Downstream Products

• 135837-63-7 3,4-dehydro-1-(9-fluorenylmethoxycarbonyl)-L-proline 
• 1385078-34-1 (2S,4R)-1-tert-butyl 2-methyl-4-(benzoylselanyl)pyrrolidine-1,2-dicarboxylate 
• 121147-97-5 1-tert-butyl 2-methyl (2S,4R)-4-azido-1,2-pyrrolidinedicarboxylate 
• 83548-50-9 C₁₈H₂₅NO₅Se 
• 284047-09-2 4-[2-(4-isopropyl-phenyl)-ethyl]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 

Relevant articles and documents

Synthetic studies toward astins A, B and C. Efficient syntheses of cis- 3,4-dihydroxyprolines and (-)-(3S,4R)-dichloroproline esters

Efficient syntheses of the esters of cis-3,4-dihydroxyprolines and the first synthesis of the ester of the rare amino acid (-)-(3S,4R)- dichloroproline from trans-4-hydroxy-L-proline are presented. The synthetic route provides easy access to several substituted prolines and cis- hydroxylated proline esters. Various types of biological activities have been associated with these substituted prolines. The role of (-)-(3S,4R)- dichloroproline in astins A, B and C is under investigation.