83584-34-3Relevant academic research and scientific papers
Pyrimidinone antibiotics - Heterocyclic analogues with improved antibacterial spectrum
Brands, Michael,Grande, Yolanda Cancho,Endermann, Rainer,Gahlmann, Reinhold,Krueger, Jochen,Raddatz, Siegfried
, p. 2641 - 2645 (2007/10/03)
We report the synthesis and pharmacological evaluation of new derivatives of the natural dipeptide antibiotic TAN 1057 A,B containing heterocycles either in the β-amino acid side chain or as mimics of the urea function. In the course of this program, we identified novel analogues that display activity towards a broader panel of Gram-positive bacteriae.
SYNTHESIS OF 4-ARYL BENZIMIDAZOLO-s-TRIAZIN-2-ONES AND 2-AROYLAMINOBENZIMIDAZOLO-1,2,4-THIADIAZOLINES
Sridevi, G.,Rao, P. Jayaprasad,Reddy, K. Kondal
, p. 965 - 972 (2007/10/02)
Reaction of 2-aminobenzimidazole with aroylisothiocyanates gave 2-aroylaminobenzimidazoles (3) and N-aroyl-N'-(benzimidazol-2-yl)-thioureas (4).The products obtained on reaction of 4 with PCl5 in POCl3 , and with oxidising agents have been identified as 4
