835880-17-6Relevant articles and documents
Selenocyclizations: Control by Coordination and by the Counterion
Khokhar, Shaista S.,Wirth, Thomas
, p. 631 - 633 (2004)
Selective cyclizations of selenium electrophiles lead to either tetrahydrofurans or lactones (see scheme), depending on the counterions and additives. Modification of the selenium electrophiles allow selective cyclizations, irrespective of the reaction conditions applied.
Catalytic asymmetric bromoetherification and desymmetrization of olefinic 1,3-diols with C2-symmetric sulfides
Ke, Zhihai,Tan, Chong Kiat,Chen, Feng,Yeung, Ying-Yeung
, p. 5627 - 5630 (2014/05/06)
An enantioselective and highly diastereoselective bromoetherification and desymmetrization of olefinic 1,3-diols has been developed using a C 2-symmetric cyclic sulfide catalyst. This methodology has been successfully applied to the synthesis of the key intermediate of an orally active antifungal drug posaconazole (Noxafil).
Nucleophile-selective selenocyclizations
Khokhar, Shaista S.,Wirth, Thomas
, p. 4567 - 4581 (2007/10/03)
Electrophilic cyclizations are one of the major strategies for cyclofunctionalizations of alkenes. Selective selenocyclizations can be performed by adjusting various factors in such reactions. The nature of the electrophile, the counterion, solvents, and
