835885-26-2Relevant academic research and scientific papers
SUBSTITUTED INDAZOLE-O-GLUCOSIDES
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Page/Page column 45, (2008/06/13)
Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1
Zhang, Xiaoyan,Urbanski, Maud,Patel, Mona,Zeck, Roxanne E.,Cox, Geoffrey G.,Bian, Haiyan,Conway, Bruce R.,Beavers, Mary Pat,Rybczynski, Philip J.,Demarest, Keith T.
, p. 5202 - 5206 (2007/10/03)
A series of benzo-fused heteroaryl-O-glucosides was synthesized and evaluated in SGLT1 and 2 cell-based functional assays. Indole-O-glucoside 10a and benzimidazole-O-glucoside 18 exhibited potent in vitro SGLT2 inhibitory activity.
