836-21-5Relevant academic research and scientific papers
CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF
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Paragraph 1165; 1166; 1167, (2016/02/21)
Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.
Chemokine receptor antagonists and methods of use thereof
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, (2008/06/13)
Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: formula (1) or physiologically acceptable salt thereof.
CCR8 INHIBITORS
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Page 26; 29, (2008/06/13)
Disclosed is an inhibitor of CCR8 that is represented by Structural Formula (I). Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent and a CCR8 inhibitor represented by Structural Formula (I). Also disclosed is a method of treating inflammatory disorders in a subject by administering a CCR8 inhibitor to the subject.
CCR8 INHIBITORS
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Page 31; 34, (2008/06/13)
Disclosed are CCR8 inhibitors represented by Structural Formulas (I). The variables in Structural Formula (I) are described herein. Also disclosed are methods of treating a subject with a CCR8 mediated condition, especially asthma, by administering one of the disclosed CCR8 inhibitors to the subject.
Chemokine receptor anagonists and methods of use therefor
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, (2008/06/13)
Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.
1-benzyl-3,5-dimethyl-4-piperdyl ester of a Hantzsch dihydropyridine
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, (2008/06/13)
The compound of the formula STR1 is disclosed to have a less rapid decrease in blood pressure in its use as an antihypertensive.
