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Dihydrocyclosporine, a synthetic derivative of cyclosporine, is a potent immunosuppressant drug primarily used to prevent organ rejection after transplantation. It functions by suppressing the immune system to prevent it from attacking the transplanted organ. With a similar mechanism of action to cyclosporine, dihydrocyclosporine is believed to possess improved stability and reduced side effects. It is often used in combination with other immunosuppressant drugs to achieve the desired level of immunosuppression while minimizing adverse effects.

83602-88-4

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  • 30-ethyl-14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhexyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,1

    Cas No: 83602-88-4

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83602-88-4 Usage

Uses

Used in Transplantation Medicine:
Dihydrocyclosporine is used as an immunosuppressant for preventing organ rejection in various types of transplantation, including kidney, liver, and heart. It helps to maintain the health of the transplanted organ by reducing the immune system's response to it.
Used in Combination Therapy:
Dihydrocyclosporine is used in combination with other immunosuppressant drugs to achieve a balanced level of immunosuppression. This approach aims to minimize the risk of organ rejection while reducing the potential for adverse effects associated with high doses of a single immunosuppressant.
However, it is important to note that, like other immunosuppressants, dihydrocyclosporine can increase the risk of infections and certain types of cancer due to its immunosuppressive properties. Therefore, patients receiving this medication should be closely monitored for any signs of infection or malignancy.

Check Digit Verification of cas no

The CAS Registry Mumber 83602-88-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,6,0 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 83602-88:
(7*8)+(6*3)+(5*6)+(4*0)+(3*2)+(2*8)+(1*8)=134
134 % 10 = 4
So 83602-88-4 is a valid CAS Registry Number.
InChI:InChI=1/C62H113N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h34-47,49-52,75H,25-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1

83602-88-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 30-ethyl-14,17,23,32-tetrahydroxy-33-(1-hydroxy-2-methylhexyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta-13,16,22,31-tetraene-2,5,8,11,20,26,29-heptaone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83602-88-4 SDS

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