83643-88-3 Usage
Uses
Different sources of media describe the Uses of 83643-88-3 differently. You can refer to the following data:
1. (S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.
2. Active enantiomer of AMPA that induces apoptosis in cortical neurons
3. (S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.
General Description
AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).
Biological Activity
Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset? .
Biochem/physiol Actions
Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 83643-88-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,6,4 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 83643-88:
(7*8)+(6*3)+(5*6)+(4*4)+(3*3)+(2*8)+(1*8)=153
153 % 10 = 3
So 83643-88-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
