83665-45-6Relevant academic research and scientific papers
Synthesis and antihypertensive activity of stereoisomers of 4-piperidyl-1,3-dihydro-2-oxo-2H-benzimidazoles. Enhanced potencies of (+) isomers
Kasuya,Shigenobu,Hashikami,Karashima,Obase,Takai,Teranishi,Karasawa,Kubo
, p. 208 - 213 (1983)
To elucidate the relationship between the pharmacological activity and stereochemical structure, we resolved 1-[2-(3,4,5-trimethoxyphenyl)-2-hydroxy-1-methylethyl]-4-(1,3-dihydro-2-ox o-2H-benzimidazol-1-yl)piperidine (1 and 2) and 1-[2-(3,4-dimethoxyphen
