83670-76-2

Basic information

• Product Name: 6,7-DIHYDROPYRANO[3,4-C]PYRROL-4(2H)-ONE
• Synonyms: 6,7-DIHYDROPYRANO[3,4-C]PYRROL-4(2H)-ONE;6,7-dihydro-4H-2l2-pyrano[3,4-c]pyrrol-4-one;6,7-dihydro-4H-2l2-pyrano[3,4-c]pyrrol-4-one
• CAS NO: 83670-76-2
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 137.14
• Mol File: 83670-76-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6,7-DIHYDROPYRANO[3,4-C]PYRROL-4(2H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-DIHYDROPYRANO[3,4-C]PYRROL-4(2H)-ONE(83670-76-2)
• EPA Substance Registry System: 6,7-DIHYDROPYRANO[3,4-C]PYRROL-4(2H)-ONE(83670-76-2)

Safety Data

• Hazardous Substances Data: 83670-76-2(Hazardous Substances Data)

Upstream product

• 3393-45-1 5,6-dihydro-pyran-2-one 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 58001-44-8 clavulanic acid 
• 83670-77-3 methyl-4-aza-8-hydroxy-6-oxo-oct-2-enoate 
• 57943-81-4 potassium clavulanate 
• 83670-73-9 methyl 3-(2-hydroxyethyl)-pyrrole-4-carboxylate 

Downstream Products

• 358732-52-2 4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrole-1-carbaldehyde 

Relevant articles and documents

Novel pyrrolyllactone and pyrrolyllactam indolinones as potent cyclin-dependent kinase 2 inhibitors

Cyclin-dependent kinases (CDKs) are essential in the control of cell cycle progression. Inhibition of CDKs represents a new approach for pharmacological intervention in the treatment of a variety of proliferative diseases, especially cancer. Based on the crystal structure of CDK2 in complex with an imidazole indolinone compound 1 (SU9516), lead optimization through modeling, synthesis, and SAR studies has led to the discovery of a novel series of pyrrolyllactone and pyrrolyllactam indolinones as potent CDK2 inhibitors.

Clavulanic acid. Rearrangement to 3,4-disubstituted pyrroles

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