837-63-8Relevant academic research and scientific papers
Electrochemically Enabled Selenium Catalytic Synthesis of 2,1-Benzoxazoles fromo-Nitrophenylacetylenes
Wang, Lin-Wei,Feng, Yu-Feng,Lin, Hong-Min,Tang, Hai-Tao,Pan, Ying-Ming
, p. 16121 - 16127 (2021/03/09)
The study reported an electrochemically mediated method for the preparation of 2,1-benzoxazoles fromo-nitrophenylacetylenes. Different from the traditional electrochemical reduction of nitro to nitroso, the nitro group directly underwent a cyclization rea
One-Pot Synthesis of Indole Derivatives from the Reaction of Nitroalkynes and Alkynes via a Mercury-Carbene Intermediate
Zheng, Min,Chen, Kai,Zhu, Shifa
, p. 4173 - 4182 (2017/09/13)
The cyclization of nitroalkyne catalyzed by Hg(OTf) 2 to produce the corresponding benzo[ c ]isoxazole in excellent yields with high selectivity is reported. On the basis of this strategy, a one-pot method to synthesize indole derivatives has been developed. In this transformation, two Hg-carbene intermediates are proposed to be involved..
Sequential Silver-Catalyzed Oxidative Cyclization Reactions of Unprotected 2-Alkynylanilines to Anthranils
Arcadi, Antonio,Chiarini, Marco,Del Vecchio, Luana,Marinelli, Fabio,Michelet, Véronique
, p. 2214 - 2222 (2017/05/01)
The full details of the original Ag-catalyzed domino oxidative cyclization reactions of unprotected 2-alkynylanilines with Oxone are described. The influences of several parameters including the substrate features, oxidant, reaction conditions, and catalyst on the reaction outcome were explored. A plausible mechanism is provided for the unusual silver-catalyzed oxidative cyclization reactions of 2-alkynylanilines to anthranils.
Silver- versus gold-catalyzed sequential oxidative cyclization of unprotected 2-alkynylanilines with oxone
Arcadi,Chiarini,Vecchio, L. Del,Marinelli,Michelet
supporting information, p. 1458 - 1461 (2016/01/25)
Unprecedented domino oxidative cyclization reactions of unprotected 2-alkynylanilines to give functionalized 4H-benzo[d][1,3]oxazin-4-one or benzisoxazole derivatives in moderate to good yields are achieved by silver vs. gold selective catalysis. The search for the optimal reaction conditions revealed the divergent catalytic activity of NaAuCl4·H2O and AgNO3.
Synthesis of α-diketones from alkylaryl- and diarylalkynes using mercuric salts
Jung, Michael E.,Deng, Gang
supporting information, p. 2142 - 2145 (2014/05/06)
Both alkylarylalkynes and diarylalkynes 1 are converted into the α-diketones 2 in good yield by the use of mercuric salts, e.g., mercuric nitrate hydrate or mercuric triflate, in the presence of water. Other mercuric salts, e.g., sulfate, chloride, acetate, or trifluoroacetate, do not provide the diketone product. A possible mechanism is proposed.
Production of 3-Benzoyl-2,1-benzisoxazoles, 2-Phenyl-4H-3,1-benzoxazin-4-ones, and Novel Quinolinone Derivatives from 2-Phenylquinolin-4(1H)-ones and Sodium Dichloroisocyanurate
Staskun, Benjamin,Es, Theodorus van
, p. 511 - 516 (2007/10/02)
A simple synthesis of certain 3-benzoyl-2,1-benzisoxazoles 6 is accomplished via treatment of the corresponding 2-phenylquinolin-4(1H)-one 1 with sodium dichloroisocyanurate 2 in methanolic aq. alkali; the isomeric 2-phenyl-4H-3,1-benzoxazin-4-one 7 is al
Novel Production of 3-Benzoyl-2,1-benzisoxazoles from 2-Phenyl-quinolin-4(1H)-ones
Staskun, Benjamin,Es, Theodorus van,Billing, David G.,Boeyens, Jan C. A.
, p. 927 - 928 (2007/10/02)
2-Phenylquinolin-4(1H)-ones 1a and 1b react with sodium dichloroisocyanurate 2 in methanolic aqueous sodium hydroxide, to afford, after acidification, 3-benzoyl-2,1-benzisoxazoles 3a and 3b (ca. 30percent).
