83702-20-9Relevant academic research and scientific papers
One-pot three-component synthesis of 2-substituted 4-aminoquinazolines
Rad-Moghadam, Kurosh,Samavi, Laleh
, p. 913 - 916 (2007/10/03)
A facile and rapid synthesis of the title compounds via one-pot reaction of 2-aminobenzonitrile, orthoesters and ammonium acetate under solvent-free and microwave condition is described.
Hydroxide-Catalyzed Synthesis of Heterocyclic Aromatic Amine Derivatives from Nitriles
Smyrl, Norman R.,Smithwick, Robert W.
, p. 493 - 496 (2007/10/02)
A generalized method for synthesizing a wide variety of heterocyclic aromatic amine derivatives from nitriles by use of hydroxide catalysts is presented.Nitrile dimers (3-aminocrotononitrile and dicyandiamide) and a dimer analog (anthranilonitrile) react with monomeric nitriles in the presence of hydroxide to form respectively, aminopyrimidines, diaminotriazines and aminoquinazolines.
