837361-46-3Relevant academic research and scientific papers
Asymmetric synthesis of 3-substituted isoindolinones: Application to the total synthesis of (+)-lennoxamine
Comins, Daniel L.,Schilling, Stefan,Zhang, Yanchen
, p. 95 - 98 (2007/10/03)
(Chemical Equation Presented) An anionic chiral auxiliary mediated asymmetric alkylation of carbamate 2 provides 3-substituted isoindolinones 4 in high ee. This methodology was used in the first asymmetric synthesis of (+)-lennoxamine.
