83769-37-3Relevant academic research and scientific papers
Synthesis of 3-fluoropyruvates from glycidic-α-cyanoesters
Chehidi,Chaabouni,Baklouti
, p. 237 - 241 (2007/10/03)
The decyanation of α-cyano-β-fluoro-α-hydroxyesters is achieved, at room temperature, by action of Ni(OAc)2. The corresponding 3-fluoropyruvates are obtained in good yields.
N-Fluorobisimide: An Efficient Reagent for the α-Fluorination of Functionalized Carbonyl Compounds
Resnati, Giuseppe,DesMarteau, Darryl D.
, p. 4925 - 4929 (2007/10/02)
The N-fluorobisimide (1) has been used in the electrophilic fluorination of the lithium enolate of esters, amides, and ketones.The corresponding α-fluorocarbonyl compounds have been obtained in good yields.The α-fluorination of β-diesters, β-diamides, β-keto esters, and β-diketones has been performed either on the neutral compounds or on the metal enolates.In this way some geminal azafluoro, chlorofluoro, fluorooxy compounds have been prepared in nearly quantitative yields.Also some α-keto esters and acids have been selectively monofluorinated in the β-position by simple treatment of the neutral compound with 1.
Methode generale d'obtention des α-ceto esters β-fluores
Ourari, Ali,Condom, Roger,Guedj, Roger
, p. 2707 - 2710 (2007/10/02)
A general method of synthesis of 3-alkyl (or aryl) 3-fluoro 2-oxo esters is described.The opening of glycidic esters with HF-pyridine (70percent w/w) followed by oxidation with Jones reagent, give the corresponding derivatives of fluoropyruvic esters in good yields.
