83780-60-3

Usage

Uses

Used in Organic Synthesis:
(2R)-2-(oxan-2-yloxy)propan-1-ol is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for the formation of new chemical bonds and the synthesis of a wide range of compounds.
Used in Pharmaceutical Industry:
(2R)-2-(oxan-2-yloxy)propan-1-ol may have potential applications in the pharmaceutical industry as a precursor for the development of new drugs. Its unique structure and functional groups can be utilized to create novel pharmaceutical compounds with potential therapeutic benefits.
Used in Cosmetic Industry:
(2R)-2-(oxan-2-yloxy)propan-1-ol may also have potential applications in the cosmetic industry, where it can be used as an ingredient in various cosmetic products. Its unique properties may contribute to the formulation of innovative cosmetic products with improved performance and benefits.

Upstream product

• 3539-40-0 Ethyl (S)-(-)-2-tetrahydropyran-2-yloxypropionate 
• 110-87-2 3,4-dihydro-2H-pyran 

Downstream Products

• 83780-62-5 (2R)-2-((tetrahydro-2H-pyran-2-yl)oxy)propyl 4-methylbenzenesulfonate 
• 89401-28-5 (2R)-1-(benzyloxy)propan-2-ol 
• 143331-41-3 (2S,12S)-(-)-2,12-bis(tetrahydropyranyloxy)-7-trityl-7-aza-4,10-dioxatridecane 
• 42274-61-3 (S)-(-)-2-(tetrahydropyranyloxy)propyl p-toluenesulfonate 

Relevant academic research and scientific papers

New Symmetrical Chiral Dibenzyl- and Diphenyl-Substituted Diamido-, Dithionoamido-, Diaza-, and Azapyridino-18-crown-6 Ligands

Eleven new chiral macrocycles (1-11, see Figure 1) of the pyridino-18-crown-6 type have been prepared.Nine diazapyridino-crown ligands contain two amide (1, R = benzyl; 4, R = phenyl), two N-methylamide (7, R = phenyl), two thionoamide (2, R = benzyl; 5,

An (S)-(+)-Lactic Acid Route to (2S,6R,8S)-2,8-Dimethyl-1,7-dioxaspiroundecane and (2S,6R,8S)-2-Ethyl-8-methyl-1,7-dioxaspiroundecane and Demonstration of their Presence in the Rectal Glandular Secretion of Bactrocera nigrotibialis (Perkin)

The chiral iodide resulting from reduction and iodination of the tetrahydropyran-2-yl ether of ethyl (S)-(+)-lactate has been engaged in a free-radical addition to acrylonitrile.The resulting protected hydroxy nitrile, on reaction with pent-4-enylmagnesium bromide afforded (S)-2-tetrahydropyran-2-yloxyundec-10-en-6-one.Oxymercuration of this hydroxy enone, under reversible conditions, employing aqueous acid-tetrahydrofuran, effected simultaneous deprotection and cyclisation, and in situ biphasic demercuration with sodium borohydride provided essentially stereochemically pure (2S,6R,8S)-2,8-dimethyl-1,7-dioxaspiroundecane .Epoxidation of the protected hydroxy enone, followed by dimethylcuprate ring-opening and cyclisation, provided a mixture of the (E,E) and the two possible (E,Z)-diastereomers of 2-ethyl-8-methyl-1,7-dioxaspiroundecane with the former being the (2S,6R,8S) stereoisomer.Separation of the (E,E) from the two (E,Z) isomers was achieved by preparative gas chromatography.GC analysis of these samples and of the rectal glandular secretion of male Bactrocera nigrobialis, using a cyclodextrin-based phase, demonstrated that (2S,6R,8S)-stereoisomers of the 2,8-dimethyl-and 2-ethyl-8-methyl-1,7-dioxaspiroundecanes were the natural products, with no detectable level of the antipodes.