83785-91-5Relevant articles and documents
Cu-Catalyzed C(sp2?H)-Trifluoromethylation of Aldehyde Hydrazones with Langlois Reagent
Aryal, Puspa,Mehta, Jatin,Prakash Reddy, V.
, p. 2018 - 2024 (2021)
The C(sp2?H)-trifluoromethylation of hydrazones would give access to the α-trifluoromethylated hydrazones that can serve as intermediates in the synthesis of pharmaceutically interesting fluorinated compounds. Herein, we demonstrate the Cu-cata
Visible Light-Induced [3+2] Cyclization Reactions of Hydrazones with Hypervalent Iodine Diazo Reagents for the Synthesis of 1-Amino-1,2,3-Triazoles
Dong, Jun-Ying,Wang, He,Mao, Shukuan,Wang, Xin,Zhou, Ming-Dong,Li, Lei
supporting information, p. 2133 - 2139 (2021/03/03)
In this study, visible-light-induced [3+2] cyclization reactions of hydrazones with hypervalent iodine diazo reagents as diazomethyl radical precursors are reported. Mild reaction conditions, a broad substrate scope, and excellent functional group compatibility were observed. Furthermore, the synthetic utility was demonstrated by gram-scale synthesis and elaboration to several value-added products. This protocol broadens the scope of diazo chemistry, and is applicable to the late-stage functionalization of natural products. (Figure presented.).
A facile synthesis of 3-alkoxy and 3-amino pyrroles
Breuil-Desvergnes, Valerie,Compain, Philippe,Vatele, Jean-Michel,Gore, Jacques
, p. 8789 - 8792 (2007/10/03)
N-Amino-3-methoxy-3-pyrrolines 2 obtained from the reaction of 1-lithio methoxyallene with arylhydrazones may be converted to either 3-methoxy pyrroles 6 or 3-amino pyrroles 7 by treatment with m-chloroperbenzoic acid or 0.25 M HCl, respectively.
