83786-46-3

Basic information

• Product Name: 4,6-Dimethyl-3-phenyl-4-(tetrahydro-furan-2-yl)-3,4-dihydro-1H-pyrimidin-2-one
• CAS NO: 83786-46-3
• Molecular Weight: 272.347
• Mol File: 83786-46-3.mol

Chemical Properties

• CAS DataBase Reference: 4,6-Dimethyl-3-phenyl-4-(tetrahydro-furan-2-yl)-3,4-dihydro-1H-pyrimidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Dimethyl-3-phenyl-4-(tetrahydro-furan-2-yl)-3,4-dihydro-1H-pyrimidin-2-one(83786-46-3)
• EPA Substance Registry System: 4,6-Dimethyl-3-phenyl-4-(tetrahydro-furan-2-yl)-3,4-dihydro-1H-pyrimidin-2-one(83786-46-3)

Safety Data

• Hazardous Substances Data: 83786-46-3(Hazardous Substances Data)

Upstream product

• 83786-49-6 4-(3-ethoxypropyl)-6-methyl-1-phenylpyrimidin-2(1H)-one 
• 109-99-9 tetrahydrofuran 
• 21139-18-4 4,6-dimethyl-1-phenyl-2-oxopyrimidine 

Relevant articles and documents

Photochemistry of Pyrimidin-2(1H)-ones: Intermolecular Hydrogen Abstraction by an Imino Group Nitrogen

Irradiation of 1-alkyl-4,6-diarylpyrimidin-2(1H)-ones (1a-c) in the presence of hydrogen donors such as acyclic or cyclic ethers (2a-d), sulphides (2e-g), and xanthene (2h) gave the C-C bonded 1:1 adducts (3)-(16) of (1) and (2), via intermolecular hydrogen atom abstraction of the excited imino nitrogen of the starting pyrimidin-2(1H)-one (1).In constrast, irradiation of 1-aryl-4,6-dialkylpyrimidin-2(1H)-one (1d) in the presence of hydrogen donors gave, predominantly, the electrocyclization product (19) in addition to the 1:1 adducts (17)-(18).

PHOTOCHEMICAL REACTION OF PYRIMIDIN-2(1H)-ONES: INTER- AND INTRAMOLECULAR HYDROGEN ABSTRACTION BY THE NITROGEN OF IMINO GROUP

Irradiation of 1-methyl-4,6-diphenylpyrimidin-2(1H)-one (1a) in acyclic or cyclic ethers afforded the C-C bonded 1:1-adducts (2a-c) of 1a and ether via intermolecular hyrogen abstraction of the excited imino nitrogen of 1a, while irradiation of 1-phenyl-4-(3-ethoxypropyl)-6-methylpyrimidin-2(1H)-one (1g) gave 1-phenyl-4,6-dimethylpyrimidin-2(1H)-one (1d) via intramolecular hydrogen abstraction of the excited imino nitrogen of 1g, in addition to 2-oxo-1,3-diazabicyclohex-5-ene derivative (3g).