83797-69-7Relevant academic research and scientific papers
Autorecycling Oxidation of Alcohols Catalysed by Pyridopyrimidines as an NAD(P)(1+) Model
Nagamatsu, Tomohisa,Yamato, Hirotake,Ono, Masami,Takarada, Shigeki,Yoneda, Fumio
, p. 2101 - 2110 (2007/10/02)
Two kinds of pyridopyrimidines as new NAD-type redox catalysts, 3,7,10-trisubstituted pyridodipyrimidine-2,4,6,8(1H,3H,7H,10H)-tetraones 6 and 3,8,10-trisubstituted pyridodipyrimidine-2,4,6(3H,7H,10H)-triones 7, have been synthesized by the condensation of 6-(substituted-amino)uracils 9 and 6-(substituted-amino)-2-phenylpyrimidin-4(3H)-ones 11 with appropriate 6-chloro-5-formyluracils 12 or 2,4,6-trichloropyrimidine-5-carbaldehyde 13 in dimethylformamide (DMF) or acetic acid.Compounds 6 and 7 have been found to oxidize a variety of alcohols under neutral conditions (in the absence of base) to yield the corresponding carbonyl compounds, catalytically with a markedly high turnover number.The oxidation yields were promoted remarkably depending upon the presence of lipophilic substituents, particularly due to the presence of longer alkyl groups at the 10-position.These catalysts are so stable that the oxidation reaction proceeds until the substrate is exhausted.
Synthesis of a Proposed Isomer of F420 having α-Glutamyl Bonding.
Kimachi, Tetsutaro,Tanaka, Kiyoshi,Yoneda, Fumio
, p. 439 - 443 (2007/10/02)
A proposed isomer of redox coenzyme F420 having α-glutamyl bonding, has been synthesized from 8-benzyloxy-10-D-ribityl-5-deazaflavin and α-L-glutamyl-L-glutamic acid moiety, by the phosphite triester approach followed by deprotection procedures.
