83805-08-7Relevant academic research and scientific papers
Novel ligands for the human histamine H1 receptor: Synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes
Ghoneim, Ola M.,Legere, Jacqueline A.,Golbraikh, Alexander,Tropsha, Alexander,Booth, Raymond G.
, p. 6640 - 6658 (2007/10/03)
This paper reports the synthesis of a novel series of (±)-2-dimethylamino- 5- and 6-phenyl-1,2,3,4-tetrahydronaphthalene derivatives (5- and 6-APTs), and, corresponding affinity, functional activity, and, molecular modeling studies with regard to drug des
Synthesis and Mesomorphic Properties of 2,6-Disubstituted Tetralins
Cereghetti, Marco,Marbet, Roman,Schleich, Kuno
, p. 1318 - 1330 (2007/10/02)
Synthesis and mesomorphic behavior of nine members of each of the two classes of 6-phenyl- and 2-phenyltetralins and five members of the 2-trans-cyclohexyltetralins are reported.The synthesis of one member of each class is described in detail.Besides the target compounds, more than twenty intermediates showed liquid crystalline properties; their transition temperatures are recorded (see Tables 1-6).
