838088-58-7Relevant academic research and scientific papers
Indolinyl-thiazole based inhibitors of scavenger receptor-BI (SR-BI)-mediated lipid transport
Dockendorff, Chris,Faloon, Patrick W.,Yu, Miao,Youngsaye, Willmen,Penman, Marsha,Nieland, Thomas J. F.,Nag, Partha P.,Lewis, Timothy A.,Pu, Jun,Bennion, Melissa,Negri, Joseph,Paterson, Conor,Lam, Garrett,Dandapani, Sivaraman,Perez, José R.,Munoz, Benito,Palmer, Michelle A.,Schreiber, Stuart L.,Krieger, Monty
, p. 375 - 380 (2015/04/27)
A potent class of indolinyl-thiazole based inhibitors of cellular lipid uptake mediated by scavenger receptor, class B, type I (SR-BI) was identified via a high-throughput screen of the National Institutes of Health Molecular Libraries Small Molecule Repo
THIAZOLE-BASED INHIBITORS OF SCAVENGER RECEPTOR BI
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Page/Page column 5; 21; 42; 46; 47, (2014/05/07)
This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral in
