83809-75-0

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, dihydro-1-(4-hydroxyphenyl)-
• CAS NO: 83809-75-0
• Molecular Formula: C10H10N2O3
• Molecular Weight: 206.19800
• Mol File: 83809-75-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, dihydro-1-(4-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, dihydro-1-(4-hydroxyphenyl)-(83809-75-0)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, dihydro-1-(4-hydroxyphenyl)-(83809-75-0)

Safety Data

• Hazardous Substances Data: 83809-75-0(Hazardous Substances Data)

Upstream product

• 123-30-8 4-amino-phenol 
• 292638-85-8 acrylic acid methyl ester 
• 57-13-6 urea 
• 70156-41-1 3-[(2-Carboxy-ethyl)-(4-hydroxy-phenyl)-amino]-propionic acid 
• 70156-40-0 N-(4-hydroxyphenyl)-β-alanine methyl ester 
• 917-61-3 sodium isocyanate 
• 32987-42-1 N-(4-hydroxyphenyl)-β-alanine 

Downstream Products

• 1310680-00-2 1-[4-(1,4-dihydro-3-hydroxy-1,4-dioxonaphthalen-2-yloxy)-phenyl]-5,6-dihydropyrimidine-2,4(1H,3H)-dione 
• 1310679-98-1 3-[1-[4-(1,4-dihydro-3-hydroxy-1,4-dioxonaphthalen-2-yloxy)phenyl]ureido]propanoic acid 
• 1310679-86-7 1-[4-(3-chloro-1,4-dihydro-1,4-dioxonaphthalen-2-yloxy)-phenyl]-5,6-dihydropyrimidine-2,4(1H,3H)-dione 
• 1310679-94-7 1,1'-[(1,4-dihydro-1,4-dioxo-2,3-naphthalenediyl)bis-(oxy-4,1-phenylene)]bis(5,6-dihydropyrimidine-2,4(1H,3H)-dione) 
• 83809-84-1 1-(3,5-dibromo-4-hydroxyphenyl)-5-bromouracil 
• 83809-81-8 1-(3,5-dibromo-4-hydroxyphenyl)uracil 
• 83809-86-3 3,5-dibromo-4-hydroxyphenylurea 
• 84440-14-2 1-(4-methoxyphenyl)-3-methyldihydrouracil 
• 84440-11-9 1-(4-allyloxyphenyl)dihydrouracil 
• 83809-78-3 1-(3,5-dibromo-4-hydroxyphenyl)-5-bromodihydrouracil 
• 83809-80-7 1-(3′,5′-dibromo-4′-hydroxyphenyl)-5,5-dibromo-2,4-dioxohexahydropyrimidine 
• 84439-98-5 N-(4-hydroxyphenyl)-N-carbamido-β-alanine 
• 84440-05-1 1-(4-acetoxyphenyl)dihydrouracil 

Relevant articles and documents

BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE

Described herein are bifunctional degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins.

SYNTHESIS AND TRANSFORMATIONS OF 1-(4-HYDROXYPHENYL)DIHYDROURACILS

N-(4-hydroxyphenyl)-β-alanine and its methyl derivatives, as well as p-hydroxy-phenylamino-β,β'-dipropionic acid, were obtained by the reaction of p-aminophenol with methyl acrylate and acrylic, methacrylic, and crotonic acids.The β-alanines were converte