1-(4-Hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione

Base Information

• Chemical Name: 1-(4-Hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione
• CAS No.: 83809-75-0
• Molecular Formula: C10H10N2O3
• Molecular Weight: 206.19800
• DSSTox Substance ID: DTXSID40510532
• Wikidata: Q82368861

Synonyms:83809-75-0;1-(4-Hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, dihydro-1-(4-hydroxyphenyl)-;1-(4-hydroxyphenyl)-1,3-diazinane-2,4-dione;SCHEMBL23142791;1-(4-hydroxyphenyl)dihydrouracil;DTXSID40510532;CY-0208;SY336142;E87264;1-(4-hydroxyphenyl)hexahydropyrimidine-2,4-dione

Chemical Property of 1-(4-Hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione

Chemical Property:

• PSA: 73.13000
• LogP: 1.17940
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 206.06914219
• Heavy Atom Count: 15
• Complexity: 272

Purity/Quality:

98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(C(=O)NC1=O)C2=CC=C(C=C2)O

Technology Process of 1-(4-Hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione

There total 6 articles about 1-(4-Hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

sodium isocyanate (917-61-3) + N-(4-hydroxyphenyl)-β-alanine (32987-42-1) → 1-(4-hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione (83809-75-0)

Guidance literature:

With hydrogenchloride; acetic acid; 1)reflux 20h 2)HCl, reflux 2h;

DOI:10.1007/BF00503202

Reference yield: 80.0%

N-(4-hydroxyphenyl)-β-alanine methyl ester (70156-40-0) + urea (57-13-6) → 1-(4-hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione (83809-75-0)

Guidance literature:

With hydrogenchloride; acetic acid; 1)reflux 20h 2)HCl, reflux 2h;

DOI:10.1007/BF00503202

Reference yield: 57.0%

3-[(2-Carboxy-ethyl)-(4-hydroxy-phenyl)-amino]-propionic acid (70156-41-1) + urea (57-13-6) → 1-(4-hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione (83809-75-0)

Guidance literature:

3-[(2-Carboxy-ethyl)-(4-hydroxy-phenyl)-amino]-propionic acid; urea; With acetic acid; for 20h; Reflux;

With hydrogenchloride; In water; for 0.5h; Reflux;

DOI:10.1007/s10593-012-1105-0

upstream raw materials:

sodium isocyanate

N-(4-hydroxyphenyl)-β-alanine

N-(4-hydroxyphenyl)-β-alanine methyl ester

urea

Downstream raw materials:

N-(4-hydroxyphenyl)-N-carbamido-β-alanine

1-(3′,5′-dibromo-4′-hydroxyphenyl)-5,5-dibromo-2,4-dioxohexahydropyrimidine

1-(3,5-dibromo-4-hydroxyphenyl)-5-bromodihydrouracil

1-(4-allyloxyphenyl)dihydrouracil

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 83809-75-0 2,4(1H,3H)-Pyrimidinedione, dihydro-1-(4-hydroxyphenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send