83824-97-9

Basic information

• Product Name: N,N-ditetradecyl-N^α-t-butoxycarbonyl-N^im-tosyl-L-histidinamide
• Synonyms: N,N-ditetradecyl-N^α-t-butoxycarbonyl-N^im-tosyl-L-histidinamide
• CAS NO: 83824-97-9
• Molecular Weight: 801.231
• Mol File: 83824-97-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-ditetradecyl-N^α-t-butoxycarbonyl-N^im-tosyl-L-histidinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-ditetradecyl-N^α-t-butoxycarbonyl-N^im-tosyl-L-histidinamide(83824-97-9)
• EPA Substance Registry System: N,N-ditetradecyl-N^α-t-butoxycarbonyl-N^im-tosyl-L-histidinamide(83824-97-9)

Safety Data

• Hazardous Substances Data: 83824-97-9(Hazardous Substances Data)

Upstream product

• 17361-44-3 ditetradecylamine 
• 65057-34-3 N^α-t-butoxycarbonyl-N^im-tosyl-L-histidine dicyclohexylamine adduct 

Downstream Products

• 83824-98-0 N,N-ditetradecyl-N^α-(6-bromohexanoyl)-L-histidinamide 
• 83824-99-1 (S)-2-Amino-N,N-ditetradecyl-3-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-propionamide 

Relevant articles and documents

Catalytic Efficiency of Functionalized Vesicles in the Transamination of Pyridoxal-5'-phosphate with a Hydrophobic Amino Acid

The transamination reaction of pyridoxal-5'-phosphate (PLP) with N-dodecyl-L-alaninamide (AlaC12) was investigated in an aqueous phosphate-borate buffer at pH 7.0, μ 0.10 (KCl), and 30.0+/-0.1 deg C in the presence of single-walled vesicles of N,N-ditetradecyl-Nα-(6-trimethylammoniohexanoyl)-L-histidinamide bromide (N+C5His2C14).The electrostatic and hydrophobic interactions between the vesicles and the reactants resulted in incorporation of PLP and AlaC12 into polar and hydrophobic domains of the vesicles, respectively, in the Schiff-base formation process.The isomerization of the aldimine Schiff-base to the correspeonding ketimine Schiff-base was confirmed to be the rate-determining step in the transamination process.The reaction site in the vesicular system was found to be equivalent in polarity to dioxane-water (7:3 v/v).However, the overall reaction rate in the vesicles was enhanced 230-fold relative to that in dioxane-water (7:3 v/v).A hydrophobic and suitably polar microenvironment constructed at the reaction site is responsible for such a marked rate-enhancement.In addition, each vesicle of N+C5His2C14 provided functional (imidazolyl) groups in its hydrogen-belt domain to catalyze the intramolecular prototropic shift to yield the ketimine Schiff-base.The microenvironmental effects of molecular assemblies of N,N-ditetradecyl-Nα-(6-trimethylammoniohexanoyl)-L-alaninamide bromide and CTAB on the overall transamination were also discussed.