83858-98-4Relevant academic research and scientific papers
Synthesis of Isotopically Labeled Tri-p-tolylamine
Kesling, Brian D.,Soederberg, Bjoern C.,Gullion, Terry
, p. 1059 - 1068 (2007/10/03)
Three isotopically labeled tri-p-tolylamines, 15N, 15N2D2, and mono-13CH3, have been prepared using zeolite mediated bromination or nitration of toluenes as one of the key steps. The obtained 4-nitrotoluenes were reduced to 4-aminotoluenes, and coupled, v
Solvent effect on relative N- and O-acidity. Inversion of the deprotonation site of 2- and 4-[(2,4,6-trinitrophenyl)amino]benzoic acids
Bagno, Alessandro,Dorigo, Fabrizio,McCrae, Patrick,Scorrano, Gianfranco
, p. 2163 - 2168 (2007/10/03)
The deprotonation equilibrium of the title compounds (1 and 2, respectively) was experimentally investigated in DMSO-water (DMSO = dimethyl sulfoxide) mixtures by means of 15N NMR relaxation, and theoretically by semiempirical (AM1) and ab init
Synthesis of three isotopomers of L-tryptophan via a combination of organic synthesis and biotechnology
Berg, E. M. M. van den,Baldew, A. U.,Goede, A. T. J. W. de,Raap, J.,Lugtenburg, J.
, p. 73 - 81 (2007/10/02)
In this paper, we report the preparation of three isotopomers of L-tryptophan on a gram scale, specifically labelled with 99percent 15N (position 1) and 99percent 13C (position 2) in the indole ring; for position 3, the incorporation was 90percent 13C.The isotopically enriched indoles were synthesized from H(15)NO3, K(13)CN and (13)CH3CN and then converted, with L-serine, into the corresponding labelled L-tryptophans using genetic manipulated E. coli bacteria, which contain high amounts of the enzyme tryptophan synthetase.The 13C-13C, 13C-1H, 13C-15N and 15N-1H coupling constants of the indoles and the tryptophans were determined from the 1H NMR and 13C NMR spectra.
Substituent Effects on One-Bond 15N-13C Couplings in N,N-Dimethylanilines and Nitrobenzenes. Effect of Steric Inhibition of Conjugation
Axenrod, T.,Watnick, C. M.,Wieder, M. J.,Duangthai, S.,Webb, G. A.,et. al
, p. 11 - 15 (2007/10/02)
The 1J(15N13C) values for a series of ring-substituted N,N-dimethylaniline-15N derivatives and a series of nitrobenzene-15N derivatives were measured from the 13C spectra.In the nitrobenzenes, small changes in 1J(15N13C) are attribut
