83859-60-3Relevant academic research and scientific papers
Selective mono addition of aryllithiums to dialdehydes by micromixing
Nagaki, Aiichiro,Yamashita, Hiroki,Takahashi, Yusuke,Ishiuchi, Satoshi,Imai, Keita,Yoshida, Jun-Ichi
supporting information, p. 71 - 73 (2018/01/26)
Micromixing enables highly selective mono addition of aryllithiums to dialdehydes. Because the unchanged formyl group in the products can be used for further transformations, the present approach serves as a powerful method for protecting-group-free synthesis.
Reductive coupling of carbonyl compounds promoted by cobalt or titanium nanoparticles
Nador, Fabiana,Mascaro, Evangelina,Castro, Melisa,Vitale, Cristian,Radivoy, Gabriel
experimental part, p. 312 - 326 (2011/06/17)
The reaction of a series of aldehydes and ketones with readily prepared cobalt or titanium nanoparticles, under mild reaction conditions, led to the obtention of different reductive dimerization products depending on the nature of the transition metal used. Cobalt nanoparticles (CoNPs) allowed the selective transformation of the starting carbonyl compounds into vicinal diols, whereas the reaction promoted by titanium nanoparticles (TiNPs) led to the formation of the corresponding alkenes. In this last case, the use of trimethylsilyl chloride (TMSCl) as additive, at 0 °C, also allowed the obtention of vicinal diols after acidic aqueous work-up. ARKAT-USA, Inc.
Enantioselective Synthesis of C2-Symmetric Diols
Quallich, George J.,Keavey, Kenneth N.,Woodall, Teresa M.
, p. 4729 - 4732 (2007/10/02)
Catalytic reduction of diketones with erythro diphenyl oxazaborolidine yielded C2-symmetric diols in high enantiomeric excess.Enantiomeric excess increased and less meso isomer was generated when borane was employed equimolar with repect to the carbonyl groups and when stoichiometric oxazaborolidine was used.
