838825-98-2Relevant academic research and scientific papers
Preparation and separation of asymmetric tripodal iron complexes of tren and selected aldehydes
Brewer, Greg,Luckett, Charles
, p. 239 - 245 (2008/10/09)
The reaction of iron salts with the Schiff bases formed from the condensation of tren and mixtures of 2-pyridinecarboxaldehyde and 6-methyl-2-pyridinecarboxaldehyde, salicylaldehyde and 2-hydroxy-5- methylbenzaldehyde, salicylaldehyde and pyrrole-2-carboxaldehyde, or salicylaldehyde and 4-methyl-5-imidazolecarboxaldehyde affords a mixture of complexes that can be represented as [FetrenLxL′y] z (x +y = 3). In the case of salicylaldehyde and 4-methyl-5- imidazolecarboxaldehyde it is possible to separate the mixture with ion exchange chromatography. Reaction of iron salts with the tripodal ligands formed from the condensation of tris-(2-aminoethyl)amine (tren) with the following mixtures of aldehydes, 2-pyridinecarboxaldehyde (py) and 6-methyl-2- pyridinecarboxaldehyde (6-CH3py), salicylaldehyde (sal) and 2-hydroxy-5-methylbenzaldehyde (5-CH3sal), salicylaldehyde and pyrrole-2-carboxaldehyde (pyr), and 4-methyl-5-imidazolecarboxaldehyde (4-CH3ImH) and salicylaldehyde yielded mixtures of all four possible iron complexes, [Fe(tren)LxL′y]z (x +y = 3), where L and L′ represent different aldehydes. Preliminary indication of mixtures of products was provided by IR and UV-Vis spectroscopy. Conclusive proof of the existence of all four components (x = 0-3) in each of the reaction mixtures is provided by mass spectroscopy. Separation of the [Fetren(sal) x(4-CH3ImH)y](ClO4)y mixture can be achieved using a Sephadex ion exchange column. Treatment of the two observed fractions with base yields greatly enriched [Fetren(sal) 2(4-CH3Im)] and [Fetren(sal)(4-CH3Im) 2], which were identified by mass spectroscopy.
