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83907-40-8

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83907-40-8 Usage

Description

SPQ is a fluorescent chloride indicator. Its fluorescence is rapidly quenched by chloride in vitro. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin , and phorbol 12-myristate 13-acetate (PMA; ) in isolated human erythrocytes. In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2. SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm.

Chemical Properties

Off-White to Tan Cyrstalline Solid

Uses

SPQ offers a simple and yet powerful method to examine and measure membrane chloride transport mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 83907-40-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,9,0 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 83907-40:
(7*8)+(6*3)+(5*9)+(4*0)+(3*7)+(2*4)+(1*0)=148
148 % 10 = 8
So 83907-40-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H15NO4S/c1-18-12-5-6-13-11(10-12)4-2-7-14(13)8-3-9-19(15,16)17/h2,4-7,10H,3,8-9H2,1H3

83907-40-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name SPQ

1.2 Other means of identification

Product number -
Other names N-sulphonatopropyl 6-methoxyquinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83907-40-8 SDS

83907-40-8Downstream Products

83907-40-8Relevant articles and documents

Microwave assisted sulfopropylation of N-heterocycles using 1,3-propane sultone

Adamczyk, Maciej,Rege, Sushil

, p. 9587 - 9588 (2007/10/03)

Dramatic rate acceleration was observed for N-sulfopropylation of heterocyclic compounds (1a-h) using 1,3-propane sultone(2) under microwave irradiation affording the N-sulfopropylated compounds (3a-h) in 68-95% yield.

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