83907-40-8 Usage
Description
SPQ is a fluorescent chloride indicator. Its fluorescence is rapidly quenched by chloride in vitro. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin , and phorbol 12-myristate 13-acetate (PMA; ) in isolated human erythrocytes. In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2. SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm.
Chemical Properties
Off-White to Tan Cyrstalline Solid
Uses
SPQ offers a simple and yet powerful method to examine and measure membrane chloride transport mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 83907-40-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,9,0 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 83907-40:
(7*8)+(6*3)+(5*9)+(4*0)+(3*7)+(2*4)+(1*0)=148
148 % 10 = 8
So 83907-40-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H15NO4S/c1-18-12-5-6-13-11(10-12)4-2-7-14(13)8-3-9-19(15,16)17/h2,4-7,10H,3,8-9H2,1H3
83907-40-8Relevant articles and documents
Microwave assisted sulfopropylation of N-heterocycles using 1,3-propane sultone
Adamczyk, Maciej,Rege, Sushil
, p. 9587 - 9588 (2007/10/03)
Dramatic rate acceleration was observed for N-sulfopropylation of heterocyclic compounds (1a-h) using 1,3-propane sultone(2) under microwave irradiation affording the N-sulfopropylated compounds (3a-h) in 68-95% yield.