83907-80-6Relevant academic research and scientific papers
One-pot synthesis of pentasubstituted pyrroles from tertiary amides and malononitrile via an indirect condensation reaction on amidic carbonyl group
Tsolomiti, Georgia,Tsolomiti, Kyriaki,Tsolomitis, Athanase
, p. 235 - 238 (2007)
An one-pot procedure for the preparation of pentasubstituted pyrrole derivatives, using tertiary acid amides-phosphorus oxychloride adducts on reaction with malononitrile, in the presence of triethylamine, is described.
On the Synthesis of 3-amino-pyrroles by Thorpe-Ziegler-Cyclization
Gewald, K.,Schaefer, H.,Bellmann, P.,Hain, U.
, p. 491 - 496 (2007/10/02)
N-Aryl and alkylaminomethylene cyanacetic acid derivatives 1 react with α-halogencarbonyl compounds 2 in the presence of potassium carbonate/sodium ethoxide to yield the substituted 3-amino-pyrroles 6.Using the same principle of cyclization pyrrole deriva
