83915-70-2

Upstream product

• 3958-60-9 2-nitrophenylmethyl bromide 
• 1269141-77-6 (1R,4R,5R,6R)-6-benzyl-4,7,7-trimethyl-6-thiabicyclo[3.2.1]octan-6-ium trifluoromethanesulfonate 
• 552-89-6 2-nitro-benzaldehyde 
• 100-52-7 benzaldehyde 
• 99366-72-0 o-nitrobenzyldimethylsulfonium bromide 

Downstream Products

• 919988-97-9 (1S)-2-(2-aminophenyl)-1-phenylethanol 
• 7577-28-8 (1S)-1-(2-aminophenyl)-2-phenylethanol 
• 919989-15-4 (1S)-1-(2-N-Boc-aminophenyl)-2-phenylethanol tert-butyl ether 
• 919989-03-0 (1S)-2-(2-N-Boc-aminophenyl)-1-phenylethanol 
• 919989-01-8 (1S)-1-(2-N-Boc-aminophenyl)-2-phenylethanol 
• 919989-18-7 (1S)-2-(2-N-methylaminophenyl)-1-phenylethanol 

Relevant academic research and scientific papers

A mild access to chiral syn 1,2-diaryl glycols by stereoselective ring opening of ortho substituted trans 2,3-diaryl-oxiranes using Amberlyst 15 in H2O/THF system

Amberlyst 15 was an efficient and green catalyst for the reaction of 2,3-diaryloxiranes with H2O in organic co-solvent to prepare glycols in high yield. Ortho substituted trans 2,3-diaryloxiranes afforded the corresponding syn glycols stereo- and enantiospecifically. Stereoselectivity appeared related to the coordination ability of the substituents, irrespective of their electronic properties. Indeed o-OCH3 and o-OBn substituted syn glycols were obtained in high stereochemical ratios (6/1 and 10/1, respectively), and o-OTIPS and o-NO2 substituted ones were obtained as exclusive products, with the same ee of the parent epoxides.

New aniline-containing amino alcohols from trans-(r,r)-2-(2-nitrophenyl)-3- phenyloxirane as useful intermediates for the synthesis of chiral ligands, bases, and benzoxazine nucleus

New enantiopure aniline-containing amino alcohols are directly derived from trans-(R,R)-2-(2-nitrophenyl)-3-phenyloxirane, by alternative regioselective double reductions. Subsequent selective alkylation procedures and derivatizations provide a rapid and

L'o-nitrobenzylidenedimethylsulfuranne: synthese, reactivite

In aqueous solution, o-nitrobenzyldimethylsulfonium bromide and the corresponding ylid give, depending upon the conditions, o-nitrobenzyl alcohol, o-nitrobenzylsulfide, or methyl o-hydroxymethylbenzyl sulfide.The o-nitrophenyloxiranes may be obtained by the reaction of nitrobenzylidenedimethylsulfurane with aldehydes in a two-phase aqueous sodium hydroxide/dichloromethane system.