84028-55-7Relevant academic research and scientific papers
Structural Reassignment and Absolute Stereochemistry of Madurastatin C1 (MBJ-0034) and the Related Aziridine Siderophores: Madurastatins A1, B1, and MBJ-0035
Tyler, Andrew R.,Mosaei, Hamed,Morton, Stephanie,Waddell, Paul G.,Wills, Corinne,McFarlane, William,Gray, Joe,Goodfellow, Michael,Errington, Jeff,Allenby, Nick,Zenkin, Nikolay,Hall, Michael J.
supporting information, p. 1558 - 1562 (2017/05/31)
The madurastatins are pentapeptide siderophores originally described as containing an unusual salicylate-capped N-terminal aziridine ring. Isolation of madurastatin C1 (1) (also designated MBJ-0034), from Actinomadura sp. DEM31376 (itself isolated from a
Structure-activity relationship of new anti-tuberculosis agents derived from oxazoline and oxazole benzyl esters
Moraski, Garrett C.,Chang, Mayland,Villegas-Estrada, Adriel,Franzblau, Scott G.,M?llmann, Ute,Miller, Marvin J.
experimental part, p. 1703 - 1716 (2010/06/19)
During the syntheses and studies of natural iron chelators (mycobactins), we serendipitously discovered that a simple, small molecule, oxazoline-containing intermediate 3 displayed surprising anti-tuberculosis activity (MIC of 7.7?μM, average). Herein we
Total Synthesis of a Mycobactin: Mycobactin S2
Maurer, Peter J.,Miller, Marvin J.
, p. 240 - 245 (2007/10/02)
The synthesis of mycobactin S2, 1 (R2, R3, R5 = H, R1, R4 = CH3) is described.Mycobactin S2 is identical with natural mycobactin S except that the long hydrocarbon chain, R1, replaced by a
