84028-79-5

Upstream product

• 84028-77-3 (3-methoxycarbonylpropionyl)methylenetriphenylphosphorane 
• 100-52-7 benzaldehyde 
• 4843-72-5 (E)-2-phenylethenyllithium 
• 292638-85-8 acrylic acid methyl ester 
• 1490-25-1 succinic acid monomethylester chloride 
• 876656-49-4 methyl 4-hydroxy-6-phenylhex-5-en-2-ynoate 
• 84028-78-4 (5-methoxy-2,5-dioxopentyl)triphenylphosphonium bromide 
• 53856-93-2 methyl 5-bromo-4-oxopentanoate 
• 75-11-6 diiodomethane 
• 42996-88-3 methyl 3-oxo-5-phenyl-4-pentenoate 

Relevant academic research and scientific papers

Mg(OMe)2 promoted allylic isomerization of γ-hydroxy-α,β-alkenoic esters to synthesize γ-ketone esters

This work concerns the Mg(OMe)2 promoted allylic isomerization of γ-hydroxy-α,β-alkenoic esters with TMEDA as an additive. The isomerization proceeded under mild conditions and afforded γ-keto esters in high yield (up to 96%) within 2 h. Both (Z)- and (E)-γ-hydroxy-α,β-alkenoic esters were tolerated under the reaction conditions. This transformation involves the in situ formation of a dienolate intermediate from the easily accessible γ-hydroxy-α,β-alkenoic ester. The in situ generated dienolate can react with benzaldehyde and undergo a practical, useful tandem allylic isomerization-Aldol reaction to afford more functionalized compounds.

Low temperature carbene transfer from alkoxychromium(0) (Fischer) carbene complexes

Irradiation at low temperatures (0°C) of alkyl-, aryl- and styryl alkoxychromium(0)carbene complexes in the presence of methyl acrylate produces a mixture of diastereomeric cyclopropanes and C-H insertion derivatives. The ratio cyclopropane/C-H insertion product is independent of the reaction conditions, while the cyclopropane cis:trans ratio strongly depends on the solvent, the selectivity increasing as the polarity of the reaction solvent does.

Difluoroboroxymolybdenum fischer carbene complexes as precursors of acyl radicals: Dimerization and trapping with electron-deficient alkenes

Pentacarbonyl acyl molybdates 1 react with boron trifluoride to give difluoroboroxy Fischer carbene complexes 2, which undergo loss of the metal fragment at room temperature to form 1,2-diketones 3, 1,2-hydroxy ketones 4, or dimers 5 through a dimerization or decarbonylation-dimerization process of acyl radicals. Decomposition of 2 in the presence of electron-deficient alkenes 11 and 18 furnishes the two-, three-, and four-component coupling products 12, 13, 19, 20, and 21.

α-methylene-5-thiazolacetic acid esters

A compound of the formula STR1 wherein Ar is phenyl optionally substituted with at least one member of the group consisting of halogen, methylenedioxy, phenyl, phenoxy, --CF3 and alkyl, alkoxy and alkylthio of 1 to 6 carbon atoms, Z is selected from the group consisting of hydrogen, chlorine, --CF3 and alkyl, alkoxy and alkylthio of 1 to 6 carbon atoms, R1 and R2 are individually alkyl of 1 to 6 carbon atoms and the exocyclic double bonds independently have (E) or (Z) geometry having fungicidal activity and a process for their preparation.

Methyl 5-(Triphenylphosphoranylidene)levulinate: A Reagent for Homologation of Aldehydes to δ-Ene γ-Keto Esters

Methyl 5-(triphenylphosphoranylidene)levulinate has been synthesized and shown to condense with aldehydes to afford E δ-ene γ-keto esters in good yield.