84047-92-7

Upstream product

• 66831-30-9 Tert-butyloxycarbonyltyrosyl-glycyl-glycyl-phenylalanyl-leucine Benzyl Ester 
• 68835-86-9 Boc-L-Tyr-Gly-Gly-L-Phe-L-Leu-OMe 
• 98908-57-7 Z(OMe)-Gly-Phe-Leu-OBzl 
• 60566-43-0 Tert-butyloxycarbonyltyrosyl-glycyl-glycine Benzyl Ester 
• 88556-53-0 Boc-Tyr-Gly-Gly-NHNH₂ 
• 3978-80-1 Boc-Tyr-OH 
• 119866-67-0 (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid 2-cyano-ethyl ester 
• 7535-56-0 N-t-butoxycarbonyl-L-phenylalanine 4-nitrophenyl ester 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 98908-58-8 Z(OMe)-Gly-Gly-Phe-Leu-OBzl 
• 119866-73-8 Boc-Tyr-Gly-Gly-Phe-Leu-OCet 
• 119866-76-1 Boc-Leu-OCet 

Downstream Products

• 84047-93-8 [(S)-1-[({[((S)-1-{(S)-1-[N'-(3-Benzyloxycarbonylamino-propionyl)-hydrazinocarbonyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 103310-91-4 [(S)-1-[({[((S)-1-{(S)-1-[N'-(3-Amino-propionyl)-hydrazinocarbonyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester; compound with acetic acid 
• 103310-92-5 N^ω-(Q-β-alanyl)enkephalin hydrazide 
• 84047-95-0 [(S)-1-({[({(S)-1-[(S)-1-(N'-{3-[3-(2-Chloro-ethyl)-ureido]-propionyl}-hydrazinocarbonyl)-3-methyl-butylcarbamoyl]-2-phenyl-ethylcarbamoyl}-methyl)-carbamoyl]-methyl}-carbamoyl)-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

PROTECTION OF THE CARBOXY GROUP IN THE FORM OF THE 2-CYANOETHYL ESTERS IN SYNTHESIS OF PEPTIDES

With the aim of studying the suitability of the 2-cyano group for the protection of carboxylic functions in peptide synthesis, we have obtained the 2-cyanoethyl esters of a number of amino acids and have studied their behavior under the conditions of peptide synthesis.The synthesis of the pentapeptide leucine-enkephalin has been performed with the use of 2-cyanoethyl protection for C-terminal carboxy groups throughout.The physicochemical characteristics of the compounds synthesized are given.