Boc-Tyr-Gly-Gly-Phe-Leu-NHNH₂

Base Information

• Chemical Name: Boc-Tyr-Gly-Gly-Phe-Leu-NHNH₂
• CAS No.: 84047-92-7
• Molecular Formula: C₃₃H₄₇N₇O₈
• Molecular Weight: 669.778
• Mol file: 84047-92-7.mol

Synonyms:Boc-Tyr-Gly-Gly-Phe-Leu-NHNH₂

Chemical Property of Boc-Tyr-Gly-Gly-Phe-Leu-NHNH₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-Tyr-Gly-Gly-Phe-Leu-NHNH₂

There total 12 articles about Boc-Tyr-Gly-Gly-Phe-Leu-NHNH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Tert-butyloxycarbonyltyrosyl-glycyl-glycyl-phenylalanyl-leucine Benzyl Ester (66831-30-9) → Boc-Tyr-Gly-Gly-Phe-Leu-NHNH2 (84047-92-7)

Guidance literature:

With hydrazine hydrate; In N,N-dimethyl-formamide; for 24h;

DOI:10.1248/cpb.37.2631

Reference yield: 86.6%

Boc-L-Tyr-Gly-Gly-L-Phe-L-Leu-OMe (68835-86-9) → Boc-Tyr-Gly-Gly-Phe-Leu-NHNH2 (84047-92-7)

Guidance literature:

With hydrazine hydrate; In N,N-dimethyl-formamide; for 24h;

Reference yield: 85.0%

Boc-Tyr-Gly-Gly-Phe-Leu-OCet (119866-73-8) → Boc-Tyr-Gly-Gly-Phe-Leu-NHNH2 (84047-92-7)

Guidance literature:

With hydrazine hydrate; In methanol; for 12h;

DOI:10.1007/BF00598586

upstream raw materials:

Tert-butyloxycarbonyltyrosyl-glycyl-glycyl-phenylalanyl-leucine Benzyl Ester

Boc-L-Tyr-Gly-Gly-L-Phe-L-Leu-OMe

Boc-Tyr-Gly-Gly-Phe-Leu-OCet

Z(OMe)-Gly-Gly-Phe-Leu-OBzl

Downstream raw materials:

[(S)-1-[({[((S)-1-{(S)-1-[N'-(3-Benzyloxycarbonylamino-propionyl)-hydrazinocarbonyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester

[(S)-1-({[({(S)-1-[(S)-1-(N'-{3-[3-(2-Chloro-ethyl)-ureido]-propionyl}-hydrazinocarbonyl)-3-methyl-butylcarbamoyl]-2-phenyl-ethylcarbamoyl}-methyl)-carbamoyl]-methyl}-carbamoyl)-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester

N^ω-(Q-β-alanyl)enkephalin hydrazide

[(S)-1-[({[((S)-1-{(S)-1-[N'-(3-Amino-propionyl)-hydrazinocarbonyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester; compound with acetic acid