840475-08-3Relevant academic research and scientific papers
(S,E)-N-[1-(3-Heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: Synthesis and KCNQ2 potassium channel opener activity
L'Heureux, Alexandre,Martel, Alain,He, Huan,Chen, Jie,Sun, Li-Qiang,Starrett, John E.,Natale, Joanne,Dworetzky, Steven I.,Knox, Ronald J.,Harden, David G.,Weaver, David,Thompson, Mark W.,Wu, Yong-Jin
, p. 363 - 366 (2007/10/03)
The synthesis and the KCNQ2 opener activity of a novel series of acrylamides are described. Replacement of the morpholinyl moiety in (S,E)-N-[1-(3-morpholinophenyl)ethyl]-3-phenylacrylamide (1) with heteroaryl groups led to the identification of (S,E)-N-1
3-Heterocyclic benzylamide derivatives as potassium channel openers
-
Page 9, (2010/02/07)
The present invention provides novel 3-heterocyclic benzylamides and related derivatives having the general Formula I wherein R1, R2, R3, R4, R5, R6, A and Het are as defined in the specifi
