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racemic cis-1-benzyloxy-7-oxabicyclo[4.1.0]heptane is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

84049-34-3

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84049-34-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 84049-34-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,0,4 and 9 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 84049-34:
(7*8)+(6*4)+(5*0)+(4*4)+(3*9)+(2*3)+(1*4)=133
133 % 10 = 3
So 84049-34-3 is a valid CAS Registry Number.

84049-34-3Downstream Products

84049-34-3Relevant articles and documents

A 3,4-Epoxypiperidine structure as a novel and simple DNA-cleavage unit

Miyashita, Kazuyuki,Park, Myunji,Adachi, Sayako,Seki, Sayori,Obika, Satoshi,Imanishi, Takeshi

, p. 1075 - 1077 (2002)

Based on the 4-hydroxy-1-azabicyclo[3.1.0]hexane structure of azinomycin, a 3,4-epoxypiperidine structure was designed as a novel and simple alkylating molecular unit, and some 3,4-epoxypiperidine derivatives were found to show DNA-cleavage activity, the structural requirements for which were revealed.

INHIBITORS OF INFLUENZA VIRUSES REPLICATION

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Paragraph 0990, (2016/10/08)

PROBLEM TO BE SOLVED: To provide inhibitors of influenza virus replication. SOLUTION: Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient comprise administering to the biological sample or patient an effective amount of a compound represented by structural formula (I) or a pharmaceutically acceptable salt thereof, where the values of structural formula (IA) are as described herein. A compound is represented by structural formula (IA) or a pharmaceutically acceptable salt thereof, where the values of structural formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle. COPYRIGHT: (C)2015,JPO&INPIT

Synthesis of functionalized octahydroindoles related to daphnyphyllum alkaloids

Dorich, Stéphane,Del Valle, Juan R.,Hanessian, Stephen

, p. 799 - 804 (2014/04/03)

Functionalized octahydroindoles were synthesized from (±)-cyclohex- 2-en-1-ol as potential intermediates for convergent syntheses of several alkaloids from plants of the Daphnyphyllum genus. Georg Thieme Verlag Stuttgart, New York.

Cycloalkane Derivatives

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Paragraph 1186; 1187, (2014/03/21)

Disclosed herein are therapeutic agents and/or preventive agents for pain or therapeutic agents and/or preventive agents for a sodium channel associated disease. The present invention provides compounds represented by the following formula (I) or pharmacologically acceptable salts thereof:

SELECTIVE KINASE INHIBITORS

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Paragraph 0702, (2013/06/06)

Provided are pyrimidine compounds for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibition Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.

Synthesis of hexahydro-1H-benzo[c]chromen-1-amines via the intramolecular ring-opening reactions of aziridines by π-nucleophiles

Pulipaka, Aravinda B.,Bergmeier, Stephen C.

, p. 1420 - 1430 (2008/12/21)

The intramolecular cyclization of aziridines with π-nucleophiles can be a useful route to a number of heterocyclic and carbocyclic systems. This methodology has been applied to the synthesis of hexahydro-1H-benzo[c]chromen-1- amines, the basic skeleton of many amaryllidaceae alkaloids. The success of the aziridine cyclization is largely dependent on the N-substitution of aziridine, with activated aziridines not undergoing the cyclization reaction. Only N-H-, N-alkyl- and N-arylaziridines underwent the cyclization reaction. The ring opening of an unactivated aziridines with a π-nucleophile is one of the first examples of such a reaction. Georg Thieme Verlag Stuttgart.

A hydrogen-bonded model of the Syn epoxidation of cyclic allylic ethers under Payne conditions

Bachmann, Christian,Gesson, Jean-Pierre,Renoux, Brigitte,Tranoy, Isabelle

, p. 379 - 382 (2007/10/03)

The syn selectivity observed for the Payne (PhCN/H2O2) epoxidation of cyclohexenyl ethers is consistent with an hydrogen-bonded model implying the allylic ether oxygen and the imino hydrogen of the in situ generated perbenzimidic acid. The geometry of the two most stable conformers, deduced from AM1 calculations. allows both hydrogen bonding and oxygen transfer.

Regiochemical control of the ring opening of 1,2-epoxides by means of chelating processes. 8. Synthesis and ring opening reactions of cis- and trans-oxides derived from 3-benzyloxycyclohexene and 2-benzyloxy-5,6-dihydro-2H-pyran

Calvani, Federico,Crotti, Paolo,Gardelli, Cristina,Pineschi, Mauro

, p. 12999 - 13022 (2007/10/02)

The regiochemical outcome of the ring opening of 1,2-epoxides bearing polar remote functionalization through chelation processes assisted by metal ions, was verified in cyclic oxirane systems having the polar functionality in an allylic position to the oxirane ring. The diastereoisomeric cis/trans epoxide pairs 5,6 and 7,8 derived from 3-benzyloxycyclohexene, and 2-benzyloxy-5,6-dihydro-2H-pyran, respectively, were prepared and several of their opening reactions were studied. The regioselectivity observed largely depends on the reaction conditions (standard or metal-assisted) and, interestingly, on the nature of the nucleophile used.

SYN-STEREOSELECTIVE EPOXIDATION OF ALLYLIC ETHERS USING CF3CO3H

McKittrick, Brian A.,Ganem, Bruce

, p. 4895 - 4898 (2007/10/02)

Good syn-stereoselectivity is observed in the epoxidation of allylic ethers with CF3CO3H, indicating a new type of hydrogen-bonded transition state.

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