84049-62-7

Upstream product

• 21210-43-5 (S)-Methyl mandelate 
• 13704-09-1 (S)-(-)-ethyl mandelate 
• 17199-29-0 (S)-Mandelic acid 

Downstream Products

• 287955-80-0 2,6-diphenyl-1,3,4-oxadiazin-5(6H)-one 

Relevant academic research and scientific papers

1,3-mandelic acid thioether derivative containing '4 - R/S - oxadiazole' structure and application thereof

1,3 Mandelic acid thioether compound containing the structure of '4 - R/S - oxadiazole' is characterized in that the structure is as shown in the general formula (In / IIn) and (In In-flight R1 A is H or Cl, R. 2 For linear alkanes C

TYROSINE KINASE INHIBITORS, COMPOSITIONS AND METHODS THERE OF

The present invention relates to compounds of Formula (I), methods of using the compounds as Trk inhibitors, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders

Construction of homochiral alkaline-lanthanide heteronuclear helicates with Na+-selective bonding in the self-assembly process

A supramolecular approach to distinguish Na+ from other biologically important metal ions was demonstrated. By designing ligands reasonably, Na+-selective bonding was achieved in the construction of homochiral alkaline-lanthanide het

Multiple Hydrogen Bonds Promoted ESIPT and AIE-active Chiral Salicylaldehyde Hydrazide

The simpler, the better! A series of simple and highly fluorescent salicylaldehyde hydrazide molecules (41 samples) have been designed and prepared. Even though these soft materials contain a very small π-conjugated system, they can go through multiple intramolecular and intermolecular hydrogen bonds promoted excited-state intramolecular proton-transfer (ESIPT) to display strong blue, green, yellow, and orange aggregation-induced emission (AIE) with large Stokes shifts (up to 184 nm) and high fluorescence quantum yields (Ф up to 0.20). Unusual mechanochromic fluorescence enhancements are also found in some solid samples. Through coordination, hydrogen and halogen bonds, these flexible molecules can be used as Mg2+ (Ф up to 0.46) probes, universal anion (Ф up to 0.14) and unprotected amino acids (Ф up to 0.16) probes, and chiral diamine (enantiomeric selectivity and Ф up to 0.36 and 0.062, respectively) receptors. Combining their advantages of AIE and biocompatibility, these low cytotoxic dyes have potential application in living cell imaging. Furthermore, the effects of different functional groups on the molecule arrangement, ESIPT, AIE, probe, and chiral recognition properties are also examined, which provide a simple and bright paradigm for the design of multiple-stimuli-responsive smart materials.

ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: (I), (II) where the definitions of the variables are provided herein.