840538-52-5 Usage
Indole ring
A core structure of the compound
An aromatic ring system consisting of a six-membered carbon ring fused to a five-membered nitrogen-containing ring, which serves as the central framework for 1H-Indol-4-ol, 3-(4-methoxyphenyl)-1-(phenylsulfonyl)-.
Phenylsulfonyl group
Attached at the 1-position
A phenyl ring (a six-membered carbon ring with delocalized pi electrons) connected to a sulfonyl group (-SO2), which is further attached to the indole ring at the first position.
4-Methoxyphenyl group
Attached at the 3-position
A phenyl ring (a six-membered carbon ring with delocalized pi electrons) with a methoxy group (-OCH3) attached to the fourth position, which is further connected to the indole ring at the third position.
Potential pharmaceutical properties
Anticancer agent
The compound has been studied for its potential as a therapeutic agent, particularly in the treatment of cancer due to its ability to interfere with cancer cell growth and proliferation.
Other biological activities
Of interest for further research and development
The compound may exhibit additional biological activities that could make it useful in the treatment of other diseases or conditions, warranting further investigation and study.
Check Digit Verification of cas no
The CAS Registry Mumber 840538-52-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,0,5,3 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 840538-52:
(8*8)+(7*4)+(6*0)+(5*5)+(4*3)+(3*8)+(2*5)+(1*2)=165
165 % 10 = 5
So 840538-52-5 is a valid CAS Registry Number.
840538-52-5Relevant academic research and scientific papers
Indole-glucosides as novel sodium glucose co-transporter 2 (SGLT2) inhibitors. Part 2
Zhang, Xiaoyan,Urbanski, Maud,Patel, Mona,Cox, Geoffrey G.,Zeck, Roxanne E.,Bian, Haiyan,Conway, Bruce R.,Beavers, Mary Pat,Rybczynski, Philip J.,Demarest, Keith T.
, p. 1696 - 1701 (2007/10/03)
A series of indole-O-glucosides and C-glucosides was synthesized and evaluated in SGLT1 and SGLT2 cell-based functional assays. Compounds 2a and 2o were identified as potent SGLT2 inhibitors and screened in ZDF rats.
