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20289-26-3 Usage

Chemical Properties

Off-White Crystalline Solid with Few Darker (Brown) Particles


Different sources of media describe the Uses of 20289-26-3 differently. You can refer to the following data:
1. Indole derivative as substrate-binding; N297Q and I300V mutants of cytochrome P 450 2A6 display expansion of substrate specificity of cytochrome P 450 2A6 to oxidize substituted indoles
2. 4-Benzyloxyindole was used in the synthesis of 4-alkyloxy-aminoalkyl indole derivatives.


4-Benzyloxyindole was used in the synthesis of 4-alkyloxy-aminoalkyl indole derivatives. Reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition Reactant for preparation of indoles by Bartoli reductive cyclization as useful intermediates in medicinal chemistry research Reactant for synthesis of carbon-11-labeled 4-aryl-4H-chromenes as new PET agents for imaging of apoptosis in cancer Reactant for preparation of HCV inhibitors. Reactant for preparation of indol-3-yl tetramethylcyclopropyl ketones as CB2 cannabinoid receptor ligands Reactant for preparation of 4-aryl-4H-chromenes as apoptosis inducers

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 7, p. 34, 1990The Journal of Organic Chemistry, 51, p. 4294, 1986 DOI: 10.1021/jo00372a037Tetrahedron Letters, 24, p. 4561, 1983 DOI: 10.1016/S0040-4039(00)85955-9

Check Digit Verification of cas no

The CAS Registry Mumber 20289-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,2,8 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 20289-26:
93 % 10 = 3
So 20289-26-3 is a valid CAS Registry Number.

20289-26-3 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (L17147)  4-Benzyloxyindole, 99%   

  • 20289-26-3

  • 250mg

  • 508.0CNY

  • Detail
  • Alfa Aesar

  • (L17147)  4-Benzyloxyindole, 99%   

  • 20289-26-3

  • 1g

  • 1257.0CNY

  • Detail
  • Aldrich

  • (246212)  4-Benzyloxyindole  98%

  • 20289-26-3

  • 246212-1G

  • 965.25CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017


1.1 GHS Product identifier

Product name 4-Benzyloxyindole

1.2 Other means of identification

Product number -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20289-26-3 SDS

20289-26-3Relevant articles and documents

Synthetic method of 4-hydroxyindole


, (2021/03/30)

The invention belongs to the technical field of organic synthesis, and particularly relates to a synthetic method of 4-hydroxyindole. Aiming at the problems existing in industrial production of 4-hydroxyindole in the prior art, the technical scheme of the invention is as follows: the method comprises the following steps: (1) protecting hydroxyl in a compound 3 by using a protective group to obtaina compound 4; (2) reacting the compound 4 with N, N-dimethylformamide dimethyl acetal to obtain a compound 5; (3) mixing the compound 5 with NH2NH2.H2O and MeOH, and carrying out a reaction to obtaina compound 6; and (4) removing the protective group of the compound 6 to obtain 4-hydroxyindole. According to the method for synthesizing 4-hydroxyindole, the cost of starting materials is low, the reaction conditions in the synthesis process are mild, operation is convenient, aftertreatment is simple, and the yield is high.

A NaH-promoted N-detosylation reaction of diverse p-toluenesulfonamides

Sun, Wanwan,Chen, Xiaobei,Hu, Ying,Geng, Huihui,Jiang, Yuanrui,Zhou, Yuxin,Zhu, Wenjing,Hu, Min,Hu, Haohua,Wang, Xingyi,Wang, Xinli,Zhang, Shilei,Hu, Yanwei

supporting information, (2020/10/05)

A NaH-mediated detosylation reaction of various Ts-protected indoles, azaheterocycles, anilines and dibenzylamine was reported. The method features cheap reagent, convenient operations, mild reaction conditions and broad substrate scope. Moreover, this study revealed that the loading of NaH in tosylation reactions of nitrogen-containing compounds with NaH as a base in DMA or DMF should be controlled due to the possibility of adverse detosylation.



Paragraph 0205, (2017/08/01)

The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.

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