84071-99-8Relevant academic research and scientific papers
Thermodynamically controlled asymmetric induction: Applications with the intramolecular Diels-Alder reaction involving a furan diene
Woo,Keay
, p. 1411 - 1414 (1994)
Treatment of a variety of optically pure IMDAF precursors, containing one asymmetric centre on the sidearm, under thermodynamic conditions with MeAlCl2 (-78°C), provides cycloadducts with up to 5 asymmetric centres of known absolute stereochemi
BAKERS' YEAST MEDIATED PREPARATION OF (S)-3-(2-FURYL)-2-METHYLPROPAN-1-OL, A BIFUNCTIONAL CHIRAL C5 ISOPRENOID SYNTHON: SYNTHESIS OF (4R,8R)-4,8-DIMETHYLDECANAL, A PHEROMONE OF TRIBOLIUM CASTANEUM
Fuganti, Claudio,Grasselli, Piero,Servi, Stefano,Hoegberg, Hans-Erik
, p. 3061 - 3066 (2007/10/02)
Bakers' yeast reduction of the α,β-unsaturated aldehyde (4), leads to the preparation of the bifunctional chiral synthon (2) in enantiomerically pure form and high chemical yield.The mechanism of the reduction is discussed.The usefulness of the chiral synthon (2) is exemplified by its transformation into optically pure (S)-3-methyl-γ-butyrolactone (8) and by the synthesis of (4R,8R)-4,8-dimethyldecanal, the pheromone of Tribolium castaneum.
