Thermodynamically controlled asymmetric induction: Applications with the intramolecular Diels-Alder reaction involving a furan diene

Article abstract of DOI:10.1016/0957-4166(94)80098-7

Treatment of a variety of optically pure IMDAF precursors, containing one asymmetric centre on the sidearm, under thermodynamic conditions with MeAlCl₂ (-78°C), provides cycloadducts with up to 5 asymmetric centres of known absolute stereochemi