84088-51-7

Basic information

• Product Name: methyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
• Synonyms: 3-Quinolinecarboxylic acid, 4-chloro-1,2-dihydro-1-methyl-2-oxo-, methyl ester
• CAS NO: 84088-51-7
• Molecular Formula: C₁₂H₁₀ClNO₃
• Molecular Weight: 251.6657
• Mol File: 84088-51-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 344.9°C at 760 mmHg
• Flash Point: 162.4°C
• Density: 1.39g/cm³
• Vapor Pressure: 6.39E-05mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: methyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate(84088-51-7)
• EPA Substance Registry System: methyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate(84088-51-7)

Safety Data

• Hazardous Substances Data: 84088-51-7(Hazardous Substances Data)

Upstream product

• 10328-92-4 N-Methylisatoic anhydride 
• 84088-50-6 4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid methyl ester 

Relevant articles and documents

Ring Closure and Rearrangement Reactions of 4-Azido-2-oxoquinoline-3-carboxylates and 4-Azidocoumarin-3-carboxylates [1]

4-Azido-2-oxoquinoline-3-carboxylates and 4-azidocoumarin-3-carboxylates 6, which were obtained from the corresponding 4-hydroxy derivatives 1 via 4-tosylates 2 or 4-chloro compounds 4, cyclized upon thermolysis to 3-alkoxyisoxazolo[4,3-c]quinolin-4(5H)-ones or the corresponding coumarins 8, whereas at slightly higher temperatures a 3-O, 4-O-rearrangement took place to give the 4-alkoxy-isoxazolo[4,3-c]-quinolin-3-ones and the corresponding coumarins 9. The necessary reaction conditions could be obtained easily with the help of differential scanning calorimetry.