84104-18-7Relevant academic research and scientific papers
A NOVEL METHOD FOR THE SYNTHESIS OF α,β-DIHYDROXY KETONES via TIN(II) ENEDIOLATES
Mukaiyama, Teruaki,Kato, Jun-ichi,Yamaguchi, Masahiko
, p. 1291 - 1294 (1982)
Activated metallic tin, prepared from stannous chloride and metallic potassium, reacts readily with α-dicarbonyl compounds to form tin(II) enediolates, which in turn react with aldehydes under a mild reaction condition to give α,β-dihydroxy ketones in good yields.The reaction proceeds stereoselectively in the presence of hexafluorobenzene.
A Facile Synthesis of 2,3-Dihydroxyketones from 1,2-Diketones and Aldehydes Using Samarium Diiodide
Miyoshi, Norikazu,Takeuchi, Seiji,Ohgo, Yoshiaki
, p. 959 - 962 (2007/10/02)
In the presence of samarium diiodide, 1,2-diketones react with aldehydes to afford the corresponding 2,3-dihydroxyketones in good yields with moderate diastereoselectivity.The reaction of unsymmetrical 1,2-diketones with aldehydes gives the products with high regioselectivities.
