84119-04-0Relevant academic research and scientific papers
Passage of Aryl-Tripped Alkyl Groups through Molecular Cavities: The Role of Flexibility
Whitlock, Barabara J.,Whitlock, Howard W.
, p. 1325 - 1329 (1985)
A series of ω-phenylalkyl esters of cyclophane 2 were synthesized.Cyclophane 2 has a cavity ca. 4.5 Angstroem by 6 Angstroem through which the phenylalkyl groups may pass.The activation energy for passage of the phenylalkyl groups through the cyclophane's cavity varies with structure in a manner which suggests dominant importance of alkyl group flexibility.These conclusions are supported by molecular mechanics calculations.
